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Strain Detail


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 Strain information
  CARD ID
719 
Type of strain Transgenic. 
Strain name C57BL/6-Tg(Acta2-DMD)2Kmk 
Internal Code mdx;B6-Tg(Acta2-Humdys)2MK(SMTg/mdx(10)),SMTg/mdx(10) 
Submitter Unknown Unknown 
Submitter affiliation or code  
Stock Type  
Material Transfer Conditions Other conditions. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization Kumamoto University Department of Child Development 
Organization code kmk 
Developer Ito Kaori, Kimura Shigemi 
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
DMD 
Gene name Dystrophin 
Allele symbol  
Allele name  
MGI  
Chromosome Unknown  
Gene classification Gene to express(transgenic) 
Method MicroInjection 
OMIM OMIM ID: 300377
Human Gene Symbol: DMD

 
 Primer 1
  PCR Primer EA-F2  TgC TCA CgA gAA CAC ATg ATA 
Dys-R2  AgT gTA TAT CAA ggC AgC gAT 
 

 Reference information
 reference information 1
  Author
Kaori Ito, Shigemi Kimura, Shiro Ozasa, Makoto Matsukura, Makoto Ikezawa, Kowashi Yoshioka, Hiroe Ueno, Misao Suzuki, Kimi Araki, Ken-ichi Yamamura, Takeshi Miwa, George Dickson, Gail D. Thomas and Teruhisa Miike 
Title Smooth muscle-specific dystrophin expression improves aberrant vasoregulation in mdx mice 
Journal Human Molecular Genetics 
Volume 15 
Page 2266-2275 
Year 2006 
PMID  
 
 Disease , Applicable field information
  Disease name,
Applicable field
Neurobiology, Anatomy, Physiology 
  OMIM OMIM ID: 300377
Human Gene Symbol: DMD
Allelic Variant Name :
DUCHENNE MUSCULAR DYSTROPHY
INTERMEDIATE MUSCULAR DYSTROPHY
BECKER MUSCULAR DYSTROPHY
CARDIOMYOPATHY, DILATED, 3B
DUCHENNE MUSCULAR DYSTROPHY, MENTAL RETARDATION, AND ABSENCE OF ERG
BECKER MUSCULAR DYSTROPHY, ATYPICAL