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Strain Detail


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 Strain information
  CARD ID
635 
Type of strain Transgenic. 
Strain name B6;C-Tg(CD2-PKCA)1Clhs 
Internal Code PKC α Tg mouse 
Submitter KAWAMOTO Yoshiyuki 
Submitter affiliation or code Chubu University Research Institute of Life and Health Sciences 
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization Nagoya University School of Medicine 
Organization code  
Developer IWAMOTO, Takashi 
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
PKCA 
Gene name Protein Kinase C, alpha 
Allele symbol  
Allele name  
MGI  
Chromosome Unknown  
Gene classification Gene to express(transgenic) 
Method MicroInjection 
OMIM OMIM ID: 176960
Human Gene Symbol: PRKCA

 

 Reference information
 reference information 1
  Author
Kozo Ohkusu, Jun Du, Ken-Ichi Isobe, Hong Yi, Anwarul A. Akhand, Masashi Kato, Haruhiko Suzuki, Hiroyoshi Hidaka, and Izumi Nakashima 
Title Protein Kinase Cα-Mediated Chronic Signal Transduction for Immunosenescence1 
Journal The Journal of Immunology 
Volume 159 
Page 2082-2084 
Year 1997 
PMID  
 
 reference information 2
  Author
Takashi Iwamoto, Masatoshi Hagiwara, Hiroyoshi Hidaka, Takeshi Isomura, Dimitris Kioussis, and Izumi Nakashima 
Title Accelerated Proliferation and Interleukin-2 Production of Thymocytes by Stimulation of Soluble Anti-CD3 Monoclonal Antibody in Transgenic Mice Carrying a Rabbit Protein Kinase Cα 
Journal THE JOURNAL OF BIOLOGICAL CHEMISTRY 
Volume 267 
Page 18644-18648 
Year 1992 
PMID  
 
 Disease , Applicable field information
  Disease name,
Applicable field
cancer, Immunology 
  OMIM OMIM ID: 176960
Human Gene Symbol: PRKCA
Allelic Variant Name :
PITUITARY TUMOR, INVASIVE, SOMATIC