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Strain Detail


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 Strain information
  CARD ID
428 
Type of strain Transgenic. 
Strain name C57BL/6N-Tg(CAG-AURKA(WT))Card 
Internal Code
C57BL/6N-Tg(CAG-AURKA(WT))Card 
Submitter Unknown Unknown 
Submitter affiliation or code  
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization Center for Animal Resources and Development, Kumamoto University 
Organization code  
Developer Misao Suzuki 
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks Unknown 
 
 Gene information
 Gene information 1
  Gene symbol
AURKA 
Gene name Aurora-kinase A (human) 
Allele symbol  
Allele name  
MGI  
Chromosome  
Gene classification Gene to express(transgenic) 
Method MicroInjection 
OMIM OMIM ID: 603072
Human Gene Symbol: AURKA

 
 Primer 1
  PCR Primer primerA  5'(Aurora-A S2: aaa gag caa gca gcc cct gc)3' 
 

 Reference information
 reference information 1
  Author
Araki, K., Araki, M., Miyazaki, J. & Vassalli, P. 
Title Site-Specific Recombination of a Transgene in Fertilized Eggs by Transient Expression of Cre Recombinase 
Journal Proc. Natl. Acad. Sci. USA 
Volume 92 
Page 160-164 
Year 1995 
PMID 7816809  
 
 reference information 2
  Author
Bischoff, J.R., Anderson, L., Zhu, Y., Mossie, K., Ng, L., Souza, B., Schryver, B., Flanagan, P., Clairvoyant, F., Ginther, C., Chan, C.S., Novotny, M., Slamon, D.J. & Plowman, G.D. 
Title A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers 
Journal Embo J 
Volume 17 
Page 3052-3065 
Year 1998 
PMID 9606188  
 
 reference information 3
  Author
Hogan, B., Beddington, R., Costantini, F., and Lacy, E. 
Title  
Journal Manipulating the Mouse Embryo: A Laboratory Manual, 2nd Edn. 
Volume  
Page  
Year 1994 
PMID  
 
 Disease , Applicable field information
  Disease name,
Applicable field
cancer 
  OMIM OMIM ID: 603072
Human Gene Symbol: AURKA
Allelic Variant Name :
COLON CANCER, SUSCEPTIBILITY TO