Center for Animal Resources and Development Database ! Home About CARD  
Strains
Genes
Reference
Disease
Download
Distribution
Home > Strains > Strain detail

Strain Detail


 - Strains   - Genes   - Reference   - Disease,Applicable field 
 Strain information
  CARD ID
400 
Type of strain Transgenic. 
Strain name C57BL/6-Tg(EF1-MCL1)12Jko 
Internal Code EA-Tg E12
C57BL/6-Tg(EF1α-MCL1)12Jko 
Submitter Unknown Unknown 
Submitter affiliation or code  
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization Keio University 
Organization code Jko 
Developer Akihiro Umezawa 
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
MCL1(Synonym:EAT) 
Gene name Myeloid cell leukemia sequence 1 (BCL2-related) (Human) 
Allele symbol  
Allele name  
MGI  
Chromosome Unknown  
Gene classification Gene to express(transgenic) 
Method MicroInjection 
OMIM OMIM ID: 159552
Human Gene Symbol: MCL1

 
 Primer 1
  PCR Primer primerA  5'(tga aga tgg tag ggt gga aag ac)3' 
primerB  5'(cac tgg cat tct tag tgc ttc tc)3' 
 

 Reference information
 reference information 1
  Author
Kenichi Matsushita, Hajime Okita, Atsushi Suzuki, Kouji Shimoda, Mariko Fukuma, Taketo Yamada, Fumihiko Urano, Takahiro Honda, Makoto Sano, Shiro Iwanaga, Satoshi Ogawa, Jun-ichi Hata, Akihiro Umezawa 
Title Islet cell hyperplasia in transgenic mice overexpressing EAT/mcl-1, a bcl-2 related gene 
Journal Molecular and Cellular Endocrinology 
Volume 203 
Page 105-116 
Year 2003 
PMID 12782407  
 
 Disease , Applicable field information
  Disease name,
Applicable field
Metabolism, cancer, Physiology 
  OMIM OMIM ID: 159552
Human Gene Symbol: MCL1