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Strain Detail


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 Strain information
  CARD ID
326 
Type of strain Targeted mutant. 
Strain name STOCK-Juntm1 
Internal Code Jun KO (hetero)
c-Jun KO 
Submitter Masahiko Hatano 
Submitter affiliation or code Graduate School of Medicine, Chiba University  
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method From other organizations.
 
Origin
(In-house)
Organization  
Organization code  
Developer  
Origin
(From other organizations)
Organization Research Institute of Molecular Pathology, Austria 
Organization code  
Developer Wagner EF 
Year introduced April 1992  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
Jun 
Gene name Jun oncogene 
Allele symbol  
Allele name  
MGI MGI:96646 
Chromosome 4 (C5-C7 cytoband , 44.6) 
Gene classification Targeted or trapped gene(knockout etc.) 
Method  
GO
GO ID GO Term GO Evidence Code
GO:0005634 nucleus IDA
GO:0005667 transcription factor complex IDA
GO:0005515 protein binding IPI
GO:0043565 sequence-specific DNA binding IEA
GO:0031953 negative regulation of protein amino acid autophosphorylation IMP
GO:0051726 regulation of cell cycle IMP
GO:0003677 DNA binding IDA
GO:0006350 transcription IEA
GO:0045449 regulation of transcription IEA
GO:0003700 transcription factor activity IEA
more... (Total Hit Count: 16)
OMIM OMIM ID: 165160
Human Gene Symbol: JUN

GO
GO ID GO Term GO Evidence Code
GO:0005634 nucleus IDA
GO:0005667 transcription factor complex IDA
GO:0005515 protein binding IPI
GO:0043565 sequence-specific DNA binding IEA
GO:0031953 negative regulation of protein amino acid autophosphorylation IMP
GO:0051726 regulation of cell cycle IMP
GO:0003677 DNA binding IDA
GO:0006350 transcription IEA
GO:0045449 regulation of transcription IEA
GO:0003700 transcription factor activity IEA
more... (Total Hit Count: 16)
 
 Primer 1
  PCR Primer primerA  5'(CACTg,AAgCg,ggAAg,ggACT,g)3' 
primerB  5'(CAATA,TCACg,ggTAg,CCAAC,g)3' 
 

 Reference information
 reference information 1
  Author
Frank Hilberg, Adriano Aguzzi, Norma Howells & Erwin F. Wagner 
Title c-Jun is essential for normal mouse development and hepatogenesis 
Journal NATURE 
Volume 365 
Page 179-181 
Year 1993 
PMID 8371760  
 
 Disease , Applicable field information
  Disease name,
Applicable field
Immunology, Development 
  OMIM OMIM ID: 165160
Human Gene Symbol: JUN