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Strain Detail


 - Strains   - Genes   - Disease,Applicable field 
 Strain information
  CARD ID
251 
Type of strain Targeted mutant. 
Strain name 129-Ttrtm1 
Internal Code Mshum1,M 
Submitter Unknown Unknown 
Submitter affiliation or code President, Shuichiro Maeda, National University Corporation University of Yamanashi 
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading, From other organizations.
 
Origin
(In-house)
Organization The First Department of Biochemistry Yamanashi Medical University 
Organization code  
Developer Shuichiro Maeda
Dr. EJ R 
Origin
(From other organizations)
Organization Columbia University 
Organization code Y4093898B1 
Developer Shuichiro Maeda
Dr. EJ R 
Year introduced August 1993  
Introduced 
Generation
N1 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
Ttr 
Gene name transthyretin 
Allele symbol Ttrtm1 
Allele name Ttr, targeted mutation 1 
MGI MGI:98865 
Chromosome 18 (7.0) 
Gene classification Targeted or trapped gene(knockout etc.) 
Method  
GO
GO ID GO Term GO Evidence Code
GO:0005179 hormone activity IEA
GO:0005576 extracellular region IEA
GO:0006810 transport IEA
OMIM OMIM ID: 176300
Human Gene Symbol: TTR

GO
GO ID GO Term GO Evidence Code
GO:0005179 hormone activity IEA
GO:0005576 extracellular region IEA
GO:0006810 transport IEA
 

 Disease , Applicable field information
  Disease name,
Applicable field
Metabolism, Neurobiology, Immunology, Development 
  OMIM OMIM ID: 176300
Human Gene Symbol: TTR
Allelic Variant Name :
AMYLOID POLYNEUROPATHY, MAHLOUDJI OR MARYLAND TYPE
TRANSTHYRETIN SER-6 POLYMORPHISM
AMYLOIDOSIS, SENILE
CARPAL TUNNEL SYNDROME, FAMILIAL
AMYLOIDOSIS, CARDIAC OR DENMARK TYPE
AMYLOID POLYNEUROPATHY, GERMAN-AMERICAN TYPE
AMYLOID POLYNEUROPATHY, JEWISH TYPE
AMYLOID POLYNEUROPATHY, RUKAVINA OR INDIANA TYPE
TRANSTHYRETIN ACIDIC ASN-90 VARIANT
AMYLOID POLYNEUROPATHY, APPALACHIAN TYPE
AMYLOID POLYNEUROPATHY, ANDRADE OR PORTUGUESE TYPE
AMYLOIDOSIS, OCULOLEPTOMENINGEAL
AMYLOID CARDIOMYOPATHY
AMYLOIDOSIS, FAMILIAL
PREALBUMIN CHICAGO
AMYLOID POLYNEUROPATHY
TRANSTHYRETIN POLYMORPHISM
AMYLOIDOSIS, SYSTEMIC, NEUROPATHIC, AND LEPTOMENINGEAL
HYPERTHYROXINEMIA, FAMILIAL DYSPREALBUMINEMIC EUTHYROID
AMYLOIDOSIS, LEPTOMENINGEAL