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Strain Detail


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 Strain information
  CARD ID
209 
Type of strain Targeted mutant. 
Strain name B10D2-Irf2tm1Isgf3gtm1 
Internal Code
B10D2-IRF9(p48)(-/-)IRF-2(-/-) 
Submitter Unknown Unknown 
Submitter affiliation or code  
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization  
Organization code  
Developer  
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
Irf2 
Gene name Interferon regulatory factor 2 
Allele symbol Irf2tm1 
Allele name Irf2, targeted mutation 1 
MGI MGI:96591 
Chromosome 8  
Gene classification Targeted or trapped gene(knockout etc.) 
Method  
GO
GO ID GO Term GO Evidence Code
GO:0006350 transcription IEA
GO:0005634 nucleus IEA
GO:0045449 regulation of transcription IEA
GO:0003677 DNA binding IEA
GO:0003700 transcription factor activity IEA
GO:0006355 regulation of transcription, DNA-dependent IEA
OMIM OMIM ID: 147576
Human Gene Symbol: IRF2

GO
GO ID GO Term GO Evidence Code
GO:0006350 transcription IEA
GO:0005634 nucleus IEA
GO:0045449 regulation of transcription IEA
GO:0003677 DNA binding IEA
GO:0003700 transcription factor activity IEA
GO:0006355 regulation of transcription, DNA-dependent IEA
 
 Gene information 2
  Gene symbol
Isgf3g (Irf-9, p48) 
Gene name interferon dependent positive acting transcription factor 3 gamma  
Allele symbol Isgf3gtm1 
Allele name Isgf3g, targeted mutation 1 
MGI MGI:107587 
Chromosome 14  
Gene classification Targeted or trapped gene(knockout etc.) 
Method  
GO
GO ID GO Term GO Evidence Code
GO:0006350 transcription IEA
GO:0045449 regulation of transcription IEA
GO:0045351 type I interferon biosynthetic process IMP
GO:0006355 regulation of transcription, DNA-dependent IEA
GO:0005634 nucleus IEA
GO:0003677 DNA binding IEA
GO:0003700 transcription factor activity IEA
OMIM OMIM ID: 147574
Human Gene Symbol: IRF9

GO
GO ID GO Term GO Evidence Code
GO:0006350 transcription IEA
GO:0045449 regulation of transcription IEA
GO:0045351 type I interferon biosynthetic process IMP
GO:0006355 regulation of transcription, DNA-dependent IEA
GO:0005634 nucleus IEA
GO:0003677 DNA binding IEA
GO:0003700 transcription factor activity IEA
 

 Reference information
 reference information 1
  Author
Toshifumi Matsuyama, Tohru Kimura, Motoo Kitagawa, Klaus Pfeffer, Takatoshi Kawakami, Nobumasa Watanabe, Thomas M. Kundig, Ryuichi Amakawa, Kenji Kishihara, Andrew Wakeham, Julia Potter, Caren L. Furlonger, Arumugavadivel Narendran, Haruhiko Suzuki, Pamela S. Ohashi, Christopher J. Paige, Tadatsugu Taniguchi, and Tak W. Mak 
Title Targeted Disruption of IRF-1 or IRF-2 Results in Abnormal Type I IFN Gene Induction and Aberrant Lymphocyte Development 
Journal Cell 
Volume 75 
Page 83-97 
Year 1993 
PMID 8402903  
 
 Disease , Applicable field information
  OMIM OMIM ID: 147576
Human Gene Symbol: IRF2

OMIM ID: 147574
Human Gene Symbol: IRF9