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Strain Detail


 - Strains   - Genes   - Reference   - Disease,Applicable field 
 Strain information
  CARD ID
202 
Type of strain Transgenic. 
Strain name BALB/cAJcl-Tg(Il2rg)M1-2 
Internal Code
BALB/cAJcl IL-2R gamma c M1-2 tg 
Submitter Unknown Unknown 
Submitter affiliation or code  
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization  
Organization code  
Developer  
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
Il2rg 
Gene name Interleukin 2 receptor, gamma chain M1-2(Mouse) 
Allele symbol  
Allele name  
MGI MGI:96551 
Chromosome Unknown  
Gene classification Gene to express(transgenic) 
Method  
GO
GO ID GO Term GO Evidence Code
GO:0016021 integral to membrane IEA
GO:0016020 membrane IEA
GO:0004872 receptor activity IEA
GO:0004896 cytokine receptor activity IEA
GO:0019976 interleukin-2 binding IPI
GO:0009897 external side of plasma membrane IDA
GO:0033089 positive regulation of T cell differentiation in the thymus IMP
GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation IMP
GO:0045579 positive regulation of B cell differentiation IMP
GO:0010468 regulation of gene expression IMP
OMIM OMIM ID: 308380
Human Gene Symbol: IL2RG

GO
GO ID GO Term GO Evidence Code
GO:0016021 integral to membrane IEA
GO:0016020 membrane IEA
GO:0004872 receptor activity IEA
GO:0004896 cytokine receptor activity IEA
GO:0019976 interleukin-2 binding IPI
GO:0009897 external side of plasma membrane IDA
GO:0033089 positive regulation of T cell differentiation in the thymus IMP
GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation IMP
GO:0045579 positive regulation of B cell differentiation IMP
GO:0010468 regulation of gene expression IMP
 

 Reference information
 reference information 1
  Author
Shiho Tsujino, James P. Di Santo, Akinori Takaoka, Teresa L. McKernan, Shigeru Noguchi, Choji Taya, Hiromichi Yonekawa, Takashi Saito, Tadatsugu Taniguchi, and Hodaka Fujii 
Title Differential requirement of the cytoplasmic subregions of γc chain in T cell Development and function 
Journal PNAS 
Volume 97 
Page 10514-10519 
Year 2000 
PMID 10962026  
 
 reference information 2
  Author
Shiho Tsujino, Tadaaki Miyazaki, Atsuo Kawahara, Michiyuki Maeda, Tadatsugu Taniguchi, and Hodaka Fujii 
Title Critical role of the membrane-proximal, proline-rich motif of the interleukin-2 receptor γc chain in the Jak3-independent signal transduction 
Journal Genes to Cells 
Volume
Page 363-373 
Year 1999 
PMID 10421845  
 
 Disease , Applicable field information
  OMIM OMIM ID: 308380
Human Gene Symbol: IL2RG
Allelic Variant Name :
SEVERE COMBINED IMMUNODEFICIENCY, X-LINKED
COMBINED IMMUNODEFICIENCY, X-LINKED