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Strain Detail


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 Strain information
  CARD ID
1524 
Type of strain Transgenic. 
Strain name BKS.NOD-Tg(hIns-TRX)90Miya 
Internal Code Ins-TRX mouse 
Submitter Miyazaki Jun-ichi 
Submitter affiliation or code Division of Stem Cell Regulation Research,Osaka University Graduate School of Medicine 
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization Osaka University Graduate School of Medicine 
Organization code Miya 
Developer Jun-ichi Miyazaki 
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
TRX 
Gene name Thioredoxin 
Allele symbol Tg(hIns-TRX)90Miya 
Allele name transgene insertion 90 Jun-ichi Miyazaki 
MGI  
Chromosome  
Gene classification Gene to express(transgenic) 
Method MicroInjection 
OMIM
 
 Primer 1
  PCR Primer BG-S0  5'-gCtggTTATTgTgCTgTCTC-3' 
hTRX-A1  5'-TCATCCACATCTACTTCAAggA-3' 
 

 Reference information
 reference information 1
  Author
Mayu Yamamoto, Eiji Yamato, Toyoda Shu-Ichi, Fumi Tashiro, Hiroshi Ikegami, Junji Yodoi, Jun-Ichi Miyazaki 
Title Transgenic Expression of Antioxidant Protein Thioredoxin in Pancreatic beta Cells Prevents Progression of Type 2 Diabetes Mellitus 
Journal Antioxidants & Redox Signaling 
Volume 10 
Page 43-50 
Year 2008 
PMID  
 
 reference information 2
  Author
Mizuo Hotta, Fumi Tashiro, Hiroshi Ikegami, Hitoshi Niwa, Toshio Ogihara, Junji Yodoi, and Jun-ichi Miyazaki 
Title Pancreatic beta Cell–specific Expression of  Thioredoxin, an Antioxidative and Antiapoptotic Protein, Prevents Autoimmune and Streptozotocin-induced Diabetes 
Journal J.Exp.Med 
Volume 188 
Page 1445-1451 
Year 1998 
PMID  
 
 Disease , Applicable field information
  Disease name,
Applicable field
Metabolism