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Strain Detail


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 Strain information
  CARD ID
131 
Type of strain Targeted mutant. 
Strain name Agttm2Smi 
Internal Code
ANG2/2 
Submitter Unknown Unknown 
Submitter affiliation or code  
Stock Type  
Material Transfer Conditions No condition. 
 
Production method From other organizations.
 
Origin
(In-house)
Organization  
Organization code  
Developer  
Origin
(From other organizations)
Organization Oliver Smithie's Labo, University of North Carolina 
Organization code Smi 
Developer  
Year introduced 1997  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
Agt 
Gene name Angiotensinogen 
Allele symbol  
Allele name  
MGI MGI:87963 
Chromosome  
Gene classification Targeted or trapped gene(knockout etc.) 
Method  
GO
GO ID GO Term GO Evidence Code
GO:0009651 response to salt stress IMP
GO:0008217 regulation of blood pressure IMP
GO:0005576 extracellular region IEA
GO:0004867 serine-type endopeptidase inhibitor activity IEA
GO:0005615 extracellular space IDA
GO:0030198 extracellular matrix organization IMP
GO:0030432 peristalsis IMP
GO:0007160 cell-matrix adhesion IMP
GO:0009409 response to cold IMP
GO:0008285 negative regulation of cell proliferation IMP
more... (Total Hit Count: 40)
OMIM OMIM ID: 106150
Human Gene Symbol: AGT

GO
GO ID GO Term GO Evidence Code
GO:0009651 response to salt stress IMP
GO:0008217 regulation of blood pressure IMP
GO:0005576 extracellular region IEA
GO:0004867 serine-type endopeptidase inhibitor activity IEA
GO:0005615 extracellular space IDA
GO:0030198 extracellular matrix organization IMP
GO:0030432 peristalsis IMP
GO:0007160 cell-matrix adhesion IMP
GO:0009409 response to cold IMP
GO:0008285 negative regulation of cell proliferation IMP
more... (Total Hit Count: 40)
 

 Reference information
 reference information 1
  Author
HYUNG-SUK KIM, JOHN H. KREGE, KIMBERLY D. KLUCKMAN, JOHN R. HAGAMAN, JEFFREY B. HODGIN, CHRISTOPHER F. BEST, J. CHARLES JENNETTE, THOMAS M. COFFMAN, NOBUYO MAEDA, AND OLIVER SMITHIES 
Title Genetic control of blood pressure and the angiotensinogen locus 
Journal Proc. Natl. Acad. Sci. USA 
Volume 92 
Page 2735-2739 
Year 1995 
PMID 7708716  
 
 Disease , Applicable field information
  OMIM OMIM ID: 106150
Human Gene Symbol: AGT
Allelic Variant Name :
RENAL TUBULAR DYSGENESIS
HYPERTENSION, ESSENTIAL, SUSCEPTIBILITY TO