| |
CARD ID
 |
1933 |
| Type of strain |
Targeted mutant. |
| Strain name |
C57BL/6-Rpt3tm1 |
| Internal Code |
Rpt3 delta |
| Submitter |
Takahashi Ryosuke |
| Submitter affiliation or code |
Department of Neurology kyoto University Graduate School of Medicine |
| Stock Type |
|
| Material Transfer Conditions |
It is necessary to consent to the submitter.
|
| Production method |
In-house breading.
|
Origin
(In-house) |
Organization |
Department of Neurology kyoto University Graduate School of Medicine |
| Organization code |
|
| Developer |
Yoshitaka Tashiro , Ryousuke Takahashi |
Origin
(From other organizations) |
Organization |
|
| Organization code |
|
| Developer |
|
| Year introduced |
|
Introduced
Generation |
|
| Remarks |
|
| |
Gene symbol
|
Psmc4 |
| Gene name |
proteasome (prosome, macropain) 26S subunit, ATPase, 4 |
| Allele symbol |
Psmc4tm1 |
| Allele name |
targeted mutation 1 |
| MGI |
MGI:1346093 |
| Chromosome |
7 (16.11) |
| Gene classification |
Targeted or trapped gene(knockout etc.) |
| Method |
MicroInjection |
| OMIM |
|
|
| |
PCR Primer |
Rpt3fl-for
|
TGAGCTGTGTATCAAGGTCC
|
|
Rpt3del-rev
|
TGCAATCCCTTGTCAGGAGA
|
|
| reference information 1 |
| |
Author
|
Tashiro Y, Urushitani M, Inoue H, Koike M, Uchiyama Y, Komatsu M, Tanaka K, Yamazaki M, Abe M, Misawa H, Sakimura K, Ito H, Takahashi R. |
| Title |
Motor Neuron-specific Disruption of Proteasomes, but not Autophagy, Replicates Amyotrophic Lateral Sclerosis. |
| Journal |
J Biol Chem. |
| Volume |
|
| Page |
PMID: 23095749 |
| Year |
2012 |
|
PMID
|
|
|
|
Disease , Applicable field information
|
| |
Disease name,
Applicable field
|
Ophthalomology, Osteosis, Dentistry, Otorhinology, Hematology, Digestive Disorders, Reproduction, Metabolism, Endocrine Disorders, Neurobiology, Dermatology, peromelia, Urology, cancer, infectious, Diabetes, Obesity, Chromosome aberration, Immunology, Genetics, Cell biology, Laboratory-animal Science, Development, Molecular biology, Pharmacology, Behavior, Aging, Anatomy, Physiology, Respiratory System
|
|
|
