| |
CARD ID
 |
1736 |
| Type of strain |
Targeted mutant. |
| Strain name |
B6;Cg-Atg5tm1Myok Spink3tm1(cre)Imeg |
| Internal Code |
Atg5 flox/-;Spink3-cre mouse |
| Submitter |
Ken-ichi YAMAMURA |
| Submitter affiliation or code |
Center for Animal Resources and Development Kumamoto University |
| Stock Type |
|
| Material Transfer Conditions |
It is necessary to consent to the submitter.
|
| Production method |
From other organizations.
|
Origin
(In-house) |
Organization |
Institute of Resource Development and Analysis, Kumamoto university |
| Organization code |
Card |
| Developer |
Ken-ichi Yamamura |
Origin
(From other organizations) |
Organization |
|
| Organization code |
|
| Developer |
|
| Year introduced |
|
Introduced
Generation |
|
| Remarks |
|
| |
Gene symbol
|
Spink3 |
| Gene name |
serine peptidase inhibitor, Kazal type 3 |
| Allele symbol |
Spink3tm1(cre)Imeg |
| Allele name |
serine peptidase inhibitor, Kazal type 3; targeted mutation 1, Institute of Molecular Embryology and Genetics |
| MGI |
|
| Chromosome |
18 (23.47) |
| Gene classification |
Targeted or trapped gene(knockout etc.) |
| Method |
|
| OMIM |
|
|
| |
Gene symbol
|
Atg5 |
| Gene name |
autophagy-related 5 |
| Allele symbol |
Atg5tm1Myok |
| Allele name |
autophagy-related 5; targeted mutation 1, Minesuke Yokoyama |
| MGI |
|
| Chromosome |
10 (23.24) |
| Gene classification |
Targeted or trapped gene(knockout etc.) |
| Method |
Electroporation |
| OMIM |
|
|
| |
PCR Primer |
check2
|
acaacgtcgagcacagctgcgcaagg
|
|
short2
|
gtactgcataatggtttaactcttgc
|
|
| |
PCR Primer |
exon3-1
|
gaatatgaaggcacacccctgaaatg
|
|
| reference information 1 |
| |
Author
|
Hashimoto D, Ohmuraya M, Hirota M, Yamamoto A, Suyama K, Ida S, Okumura Y, Takahashi E, Kido H, Araki K, Baba H, Mizushima N, Yamamura K. |
| Title |
Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells. |
| Journal |
J Cell Biol. |
| Volume |
181 |
| Page |
1065-72 |
| Year |
2008 |
|
PMID
|
|
|
| reference information 2 |
| |
Author
|
Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, Suzuki-Migishima R, Yokoyama M, Mishima K, Saito I, Okano H, Mizushima N |
| Title |
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. |
| Journal |
Nature |
| Volume |
441 |
| Page |
885-9 |
| Year |
2006 |
|
PMID
|
|
|
|
Disease , Applicable field information
|
| |
Disease name,
Applicable field
|
Digestive Disorders
|
|
|
