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Strain Detail

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Strain information

	CARD ID		396
	Type of strain		Transgenic.
	Strain name		B6;D2-Tg(CAG-PABPN1)M43Imeg
	Internal Code		M43 B6;D2-Tg(CAG-PABPN1)M43Imeg
	Submitter		Ken-ichi YAMAMURA
	Submitter affiliation or code		Center for Animal Resources and Development Kumamoto University
	Stock Type
	Material Transfer Conditions		It is necessary to consent to the submitter.
	Production method		In-house breading.
	Origin (In-house)	Organization	Institute of Molecular Embryology and Genetics
		Organization code	Imeg
		Developer	Kimi Araki
	Origin (From other organizations)	Organization
		Organization code
		Developer
		Year introduced
		Introduced Generation
	Remarks

Gene information

Gene information 1

Gene symbol

PABPN1

Gene name

Poly A Binding Protein, nuclear 1 (PABPN 1)

Allele symbol

Allele name

MGI

Chromosome

Gene classification

Gene to express(transgenic)

Method

MicroInjection

GO

GO ID	GO Term	GO Evidence Code
GO:0005737	cytoplasm	IEA
GO:0005634	nucleus	IEA
GO:0003723	RNA binding	IEA
GO:0006397	mRNA processing	IEA
GO:0003676	nucleic acid binding	IEA
GO:0000166	nucleotide binding	IEA
GO:0008143	poly(A) RNA binding	TAS
GO:0006378	mRNA polyadenylation	TAS

OMIM

OMIM ID: 602279
Human Gene Symbol: PABPN1

GO

GO ID	GO Term	GO Evidence Code
GO:0005737	cytoplasm	IEA
GO:0005634	nucleus	IEA
GO:0003723	RNA binding	IEA
GO:0006397	mRNA processing	IEA
GO:0003676	nucleic acid binding	IEA
GO:0000166	nucleotide binding	IEA
GO:0008143	poly(A) RNA binding	TAS
GO:0006378	mRNA polyadenylation	TAS

Primer 1

	PCR Primer	primerA	5'(ACCTT,CTGAT,AGGCC,G)3'
		primerB	5'(AACAG,CAGAA,GAGCT,GGAAG)3'

Reference information

reference information 1

	Author	Hirotake Hino, Kimi Araki, Eiichiro Uyama, Motohiro Takeya, Masatake Araki, Kumiko Yoshinobu, Koichiro Miike, Yasuhiro Kawazoe, Yasushi Maeda, Makoto Uchino and Ken-ichi Yamamura
	Title	Myopathy phenotype in transgenic mice expressing mutated PABPN1 as a model of oculopharyngeal muscular dystrophy
	Journal	Human Molecular Genetics
	Volume	13
	Page	181-190
	Year	2004
	PMID	14645203

Disease , Applicable field information

OMIM

OMIM ID: 602279
Human Gene Symbol: PABPN1
Allelic Variant Name :

•	OCULOPHARYNGEAL MUSCULAR DYSTROPHY