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Strain Detail


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 Strain information
  CARD ID
35 
Type of strain Gene trap. 
Strain name B6;CB-Cdk6GtAyu8104Imeg 
Internal Code
Ayu8104 
Submitter Ken-ichi YAMAMURA 
Submitter affiliation or code Center for Animal Resources and Development Kumamoto University 
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization Imeg 
Organization code Imeg 
Developer Ken-ichi Yamamura 
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
c-crk 
Gene name Proto-oncogene c-crk 
Allele symbol  
Allele name  
MGI MGI:88508 
Chromosome 11  
Gene classification Targeted or trapped gene(knockout etc.) 
Method Other 
GO
GO ID GO Term GO Evidence Code
GO:0005737 cytoplasm IEA
GO:0016020 membrane IEA
GO:0016301 kinase activity IEA
GO:0005886 plasma membrane IEA
GO:0005070 SH3/SH2 adaptor activity IPI
GO:0005515 protein binding IPI
GO:0045309 protein phosphorylated amino acid binding IDA
OMIM OMIM ID: 164762
Human Gene Symbol: CRK

GO
GO ID GO Term GO Evidence Code
GO:0005737 cytoplasm IEA
GO:0016020 membrane IEA
GO:0016301 kinase activity IEA
GO:0005886 plasma membrane IEA
GO:0005070 SH3/SH2 adaptor activity IPI
GO:0005515 protein binding IPI
GO:0045309 protein phosphorylated amino acid binding IDA
 
 Primer 1
  PCR Primer primerA  (1)5'-gcg tta ccc aac tta atc g-3' 
primerB  (2)5'-tgt gag cga gta aca acc-3' 
 

 Reference information
 reference information 1
  Author
Kimi ARAKI, Takashi IMAIZUMI, Tomohisa SEKIMOTO, kumiko YOSHINOBU, Junichiro YOSHIMUTA, Miwa AKIZUKI, Katsutaka MIURA, Masatake ARAKI and Ken-ichi YAMAMURA 
Title EXCHANGEABLE GENE TRAP USING THE Cre/MUTATED Lox SYSTEM 
Journal Cellular and Molecular BiologyTM 
Volume 45 
Page 737-750 
Year 1999 
PMID 10512203  
 
 reference information 2
  Author
Takashi Imaizumi, Kimi Araki, Katsutaka Miura, Masatake Araki, Misao Suzuki, Hidenori Terasaki and Ken-ichi Yamamura 
Title Mutant Mice Lacking Crk-II Caused by the Gene Trap Insertional Mutagenesis: Crk-II Is Not Essential for Embryonic Development 
Journal Biochemical and Biophysical Research Communications 
Volume 266 
Page 569-574 
Year 1999 
PMID 10600543  
 
 Disease , Applicable field information
  OMIM OMIM ID: 164762
Human Gene Symbol: CRK

 
 Inspection information
  Inspection
(now printing)