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Strain Detail

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Strain information

	CARD ID		2034
	Type of strain		Targeted mutant.
	Strain name		C57BL/6-Hbegf ^tm1
	Internal Code		HB^hz
	Submitter		Unknown Unknown
	Submitter affiliation or code
	Stock Type
	Material Transfer Conditions		It is necessary to consent to the submitter.
	Production method		In-house breading.
	Origin (In-house)	Organization	Osaka University, Research Institute for Microbial Diseases
		Organization code
		Developer	Eisuke Mekada
	Origin (From other organizations)	Organization
		Organization code
		Developer
		Year introduced
		Introduced Generation
	Remarks

Gene information

Gene information 1

	Gene symbol		Hbegf
	Gene name		heparin-binding EGF-like growth factor
	Allele symbol		Hbegf^tm1
	Allele name		heparin-binding EGF-like growth factor, targeted mutation 1
	MGI		MGI:96070
	Chromosome		18 (19.46 )
	Gene classification		Targeted or trapped gene(knockout etc.)
	Method
	OMIM

Primer 1

	PCR Primer	Intron3 Fw3	CAT GGG GTT GTG ACT CTC CT
		Intron3 Rev3	AGC CTG CAC ACA CAA AAG TG

Primer 2

	PCR Primer	GFP Fwd	CAA GCA GAT CCT GAA GAA CA
		GFP Rev	GAA CAT CTC CTC GAT CAG GT

Reference information

reference information 1

	Author	Tomoko Ichise1, Satoshi Adachi1, Minako Ohishi1, Masahito Ikawa2, Masaru Okabe2, Ryo Iwamoto1, and Eisuke Mekada
	Title	Humanized gene replacement in mice reveals the contribution of cancer stroma-derived HB-EGF to tumor growth
	Journal
	Volume
	Page
	Year
	PMID