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Strain Detail


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 Strain information
  CARD ID
398 
Type of strain Spontaneous/Chemical induced mutant. 
Strain name C3101F1-Pax6Sey-3H 
Internal Code
C3H/HeNCrj-Pax6Sey-3H 
Submitter Nitta Yumiko 
Submitter affiliation or code Ros.Inst. Radiat.Biot.Med., Hiroshima University 
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization  
Organization code  
Developer  
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
Pax6 
Gene name paired box gene 6 
Allele symbol  
Allele name  
MGI MGI:97490 
Chromosome 2  
Gene classification Other gene(mutant etc.) 
Method  
GO
GO ID GO Term GO Evidence Code
GO:0005634 nucleus IDA
GO:0006350 transcription IEA
GO:0005667 transcription factor complex TAS
GO:0003700 transcription factor activity TAS, IDA
GO:0003677 DNA binding IDA
GO:0007275 multicellular organismal development IEA
GO:0030154 cell differentiation IMP
GO:0007411 axon guidance IMP
GO:0030334 regulation of cell migration IMP
GO:0008285 negative regulation of cell proliferation IMP
more... (Total Hit Count: 57)
OMIM OMIM ID: 607108
Human Gene Symbol: PAX6

GO
GO ID GO Term GO Evidence Code
GO:0005634 nucleus IDA
GO:0006350 transcription IEA
GO:0005667 transcription factor complex TAS
GO:0003700 transcription factor activity TAS, IDA
GO:0003677 DNA binding IDA
GO:0007275 multicellular organismal development IEA
GO:0030154 cell differentiation IMP
GO:0007411 axon guidance IMP
GO:0030334 regulation of cell migration IMP
GO:0008285 negative regulation of cell proliferation IMP
more... (Total Hit Count: 57)
 
 Primer 1
  PCR Primer primerA  5'(gtg ggg gtg ata cct gag g)3' 
primerB  3'(aga cag acc tgt agt gaa att gtc a)5' 
 

 Reference information
 reference information 1
  Author
Ando, Yuichi; Beck, Yoshifumi; Tomikawa, Shinji; Eriguchi, Masazumi; Muto, Tetsuichiro; Takiguchi, Masafumi 
Title CELL-MEDIATED GRAFT REJECTION OBSERVED IN TWO LINES OF HUMAN HISTOCOMPATIBILITY LEUKOCYTE ANTIGEN CLASS I TRANSGENIC MICE1 
Journal Transplantation 
Volume 68 
Page 904-908 
Year 1999 
PMID 10515394  
 
 Disease , Applicable field information
  OMIM OMIM ID: 607108
Human Gene Symbol: PAX6
Allelic Variant Name :
ECTOPIA PUPILLAE
FOVEAL HYPOPLASIA WITH ANTERIOR SEGMENT ANOMALIES
ANIRIDIA
CATARACTS, CONGENITAL, WITH LATE-ONSET CORNEAL DYSTROPHY
KERATITIS, AUTOSOMAL DOMINANT
PETERS ANOMALY
ANIRIDIA, CEREBELLAR ATAXIA, AND MENTAL DEFICIENCY
OPTIC NERVE APLASIA, BILATERAL
COLOBOMA OF OPTIC NERVE
OPTIC NERVE HYPOPLASIA, BILATERAL
MORNING GLORY DISC ANOMALY
FOVEAL HYPOPLASIA, ISOLATED
FOVEAL HYPOPLASIA AND PRESENILE CATARACT SYNDROME