| |
CARD ID
 |
2062 |
| Type of strain |
Targeted mutant. |
| Strain name |
B6;129-Rab8atm1 Rab8btm1 |
| Internal Code |
rab8a,rab8b double knockout mouse |
| Submitter |
- - |
| Submitter affiliation or code |
- |
| Stock Type |
|
| Material Transfer Conditions |
It is necessary to consent to the submitter.
|
| Production method |
In-house breading.
|
Origin
(In-house) |
Organization |
I.M.C.R., Gunma Univ, |
| Organization code |
|
| Developer |
Akihiro Harada |
Origin
(From other organizations) |
Organization |
|
| Organization code |
|
| Developer |
|
| Year introduced |
|
Introduced
Generation |
|
| Remarks |
|
| |
Gene symbol
|
Rab8a |
| Gene name |
RAB8A, member RAS oncogene family |
| Allele symbol |
Rab8atm1 |
| Allele name |
RAB8A, member RAS oncogene family, targeted mutation 1 |
| MGI |
MGI:96960 |
| Chromosome |
8 (34.84) |
| Gene classification |
Targeted or trapped gene(knockout etc.) |
| Method |
Electroporation |
| OMIM |
|
|
| |
Gene symbol
|
Rab8b |
| Gene name |
RAB8B, member RAS oncogene family |
| Allele symbol |
Rab8btm1 |
| Allele name |
RAB8B, member RAS oncogene family, targeted mutation 1 |
| MGI |
MGI:2442982 |
| Chromosome |
9 (36.17) |
| Gene classification |
Targeted or trapped gene(knockout etc.) |
| Method |
Electroporation |
| OMIM |
|
|
| |
PCR Primer |
8bWT-S
|
GTT GGA CAT CTC TTC ACC TAT GC
|
|
8bWT-AS
|
CAG AAG CCC TTC CTC GTT CCT GG
|
|
| reference information 1 |
| |
Author
|
Sato T, Mushiake S, Kato Y, Sato K, Sato M, Takeda N, Ozono K, Miki K, Kubo Y, Tsuji A, Harada R, Harada A. |
| Title |
The Rab8 GTPase regulates apical protein localization in intestinal cells. |
| Journal |
Nature |
| Volume |
448 |
| Page |
366-369 |
| Year |
2007 |
|
PMID
|
|
|
| reference information 2 |
| |
Author
|
Takashi Sato, Tomohiko Iwano, Masataka Kunii, Shinji Matsuda, Rumiko Mizuguchi, Yongwook Jung, Haruo Hagiwara, Yoshihiro Yoshihara, Michisuke Yuzaki, Reiko Harada and Akihiro Harada |
| Title |
Rab8a and Rab8b are essential for multiple apical transport pathways but insufficient for ciliogenesis |
| Journal |
Journal of Cell Science |
| Volume |
|
| Page |
|
| Year |
in press |
|
PMID
|
|
|
|
Disease , Applicable field information
|
| |
Disease name,
Applicable field
|
Metabolism, Neurobiology, Cell biology, Anatomy, Physiology
|
|
|
