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Strain Detail

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Strain information

	CARD ID		718
	Type of strain		Gene trap.
	Strain name		B6-Cd99^{Gt(pU-21T)44Imeg}
	Internal Code		Ayu21-B6T44
	Submitter		Masatake ARAKI
	Submitter affiliation or code		Gene Technology Center, Kumamoto University
	Stock Type
	Material Transfer Conditions		Other conditions.
	Production method		In-house breading.
	Origin (In-house)	Organization	Institute of Molecular Embryology and Genetics Kumamoto University
		Organization code	Imeg
		Developer	Kimi Araki
	Origin (From other organizations)	Organization
		Organization code
		Developer
		Year introduced
		Introduced Generation
	Remarks

Gene information

Gene information 1

Gene symbol

Cd99 (synonym: Pilr-1)

Gene name

CD99 antigen

Allele symbol

Allele name

MGI

Chromosome

4

Gene classification

Targeted or trapped gene(knockout etc.)

Method

Electroporation

GO

GO ID	GO Term	GO Evidence Code
GO:0005515	protein binding	IPI
GO:0016020	membrane	IEA
GO:0016021	integral to membrane	IEA

OMIM

OMIM ID: 313470
Human Gene Symbol: CD99

OMIM ID: 450000
Human Gene Symbol: CD99

GO

GO ID	GO Term	GO Evidence Code
GO:0005515	protein binding	IPI
GO:0016020	membrane	IEA
GO:0016021	integral to membrane	IEA

Primer 1

	PCR Primer	Z-1	GCGTTACCACCTTAATCG
		Z-2	TGTGAGCGATAACAACC

Reference information

reference information 1

	Author	Hyo Jin Park, et al.
	Title	CD99-Dependent Expansion of Myeloid-Derived Suppressor Cells and Attenuation of Graft-Versus-Host Disease.
	Journal	Molecules and Cells
	Volume	33
	Page	259-267
	Year	2012
	PMID

reference information 2

	Author	Girl Nam, et al.
	Title	Interaction of CD99 with its paralog CD99L2 positively regulates CD99L2 trafficking to cell surfaces.
	Journal	J. Immunology
	Volume	191
	Page	5730-5742
	Year	2013
	PMID

reference information 3

	Author	Goswami, D., Marz, et al.
	Title	Endothelial CD99 supports arrest of mouse neutrophils in venules and binds to neutrophil PILRs.
	Journal	Blood
	Volume	129
	Page	1811-1822
	Year	2017
	PMID

Disease , Applicable field information

	Disease name, Applicable field	Immunology, Development
	OMIM	OMIM ID: 313470 Human Gene Symbol: CD99 OMIM ID: 450000 Human Gene Symbol: CD99

Related imformation

EGTC

21-B6T44