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Strain Detail


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 Strain information
  CARD ID
396 
Type of strain Transgenic. 
Strain name B6;D2-Tg(CAG-PABPN1)M43Imeg 
Internal Code M43
B6;D2-Tg(CAG-PABPN1)M43Imeg 
Submitter Ken-ichi YAMAMURA 
Submitter affiliation or code Center for Animal Resources and Development Kumamoto University 
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization Institute of Molecular Embryology and Genetics 
Organization code Imeg 
Developer Kimi Araki 
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
PABPN1 
Gene name Poly A Binding Protein, nuclear 1 (PABPN 1) 
Allele symbol  
Allele name  
MGI MGI:1859158 
Chromosome  
Gene classification Gene to express(transgenic) 
Method MicroInjection 
GO
GO ID GO Term GO Evidence Code
GO:0005737 cytoplasm IEA
GO:0005634 nucleus IEA
GO:0003723 RNA binding IEA
GO:0006397 mRNA processing IEA
GO:0003676 nucleic acid binding IEA
GO:0000166 nucleotide binding IEA
GO:0008143 poly(A) RNA binding TAS
GO:0006378 mRNA polyadenylation TAS
OMIM OMIM ID: 602279
Human Gene Symbol: PABPN1

GO
GO ID GO Term GO Evidence Code
GO:0005737 cytoplasm IEA
GO:0005634 nucleus IEA
GO:0003723 RNA binding IEA
GO:0006397 mRNA processing IEA
GO:0003676 nucleic acid binding IEA
GO:0000166 nucleotide binding IEA
GO:0008143 poly(A) RNA binding TAS
GO:0006378 mRNA polyadenylation TAS
 
 Primer 1
  PCR Primer primerA  5'(ACCTT,CTGAT,AGGCC,G)3' 
primerB  5'(AACAG,CAGAA,GAGCT,GGAAG)3' 
 

 Reference information
 reference information 1
  Author
Hirotake Hino, Kimi Araki, Eiichiro Uyama, Motohiro Takeya, Masatake Araki, Kumiko Yoshinobu, Koichiro Miike, Yasuhiro Kawazoe, Yasushi Maeda, Makoto Uchino and Ken-ichi Yamamura 
Title Myopathy phenotype in transgenic mice expressing mutated PABPN1 as a model of oculopharyngeal muscular dystrophy 
Journal Human Molecular Genetics 
Volume 13 
Page 181-190 
Year 2004 
PMID 14645203  
 
 Disease , Applicable field information
  OMIM OMIM ID: 602279
Human Gene Symbol: PABPN1
Allelic Variant Name :
OCULOPHARYNGEAL MUSCULAR DYSTROPHY