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Strain Detail

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Strain information

	CARD ID		209
	Type of strain		Targeted mutant.
	Strain name		B10D2-Irf2^tm1Isgf3g^tm1
	Internal Code		B10D2-IRF9(p48)(-/-)IRF-2(-/-)
	Submitter		Unknown Unknown
	Submitter affiliation or code
	Stock Type
	Material Transfer Conditions		It is necessary to consent to the submitter.
	Production method		In-house breading.
	Origin (In-house)	Organization
		Organization code
		Developer
	Origin (From other organizations)	Organization
		Organization code
		Developer
		Year introduced
		Introduced Generation
	Remarks

Gene information

Gene information 1

Gene symbol

Irf2

Gene name

Interferon regulatory factor 2

Allele symbol

Irf2^tm1

Allele name

Irf2, targeted mutation 1

MGI

Chromosome

8

Gene classification

Targeted or trapped gene(knockout etc.)

Method

GO

GO ID	GO Term	GO Evidence Code
GO:0006350	transcription	IEA
GO:0005634	nucleus	IEA
GO:0045449	regulation of transcription	IEA
GO:0003677	DNA binding	IEA
GO:0003700	transcription factor activity	IEA
GO:0006355	regulation of transcription, DNA-dependent	IEA

OMIM

OMIM ID: 147576
Human Gene Symbol: IRF2

GO

GO ID	GO Term	GO Evidence Code
GO:0006350	transcription	IEA
GO:0005634	nucleus	IEA
GO:0045449	regulation of transcription	IEA
GO:0003677	DNA binding	IEA
GO:0003700	transcription factor activity	IEA
GO:0006355	regulation of transcription, DNA-dependent	IEA

Gene information 2

Gene symbol

Isgf3g (Irf-9, p48)

Gene name

interferon dependent positive acting transcription factor 3 gamma

Allele symbol

Isgf3g^tm1

Allele name

Isgf3g, targeted mutation 1

MGI

Chromosome

14

Gene classification

Targeted or trapped gene(knockout etc.)

Method

GO

GO ID	GO Term	GO Evidence Code
GO:0006350	transcription	IEA
GO:0045449	regulation of transcription	IEA
GO:0045351	type I interferon biosynthetic process	IMP
GO:0006355	regulation of transcription, DNA-dependent	IEA
GO:0005634	nucleus	IEA
GO:0003677	DNA binding	IEA
GO:0003700	transcription factor activity	IEA

OMIM

OMIM ID: 147574
Human Gene Symbol: IRF9

GO

GO ID	GO Term	GO Evidence Code
GO:0006350	transcription	IEA
GO:0045449	regulation of transcription	IEA
GO:0045351	type I interferon biosynthetic process	IMP
GO:0006355	regulation of transcription, DNA-dependent	IEA
GO:0005634	nucleus	IEA
GO:0003677	DNA binding	IEA
GO:0003700	transcription factor activity	IEA

Reference information

reference information 1

	Author	Toshifumi Matsuyama, Tohru Kimura, Motoo Kitagawa, Klaus Pfeffer, Takatoshi Kawakami, Nobumasa Watanabe, Thomas M. Kundig, Ryuichi Amakawa, Kenji Kishihara, Andrew Wakeham, Julia Potter, Caren L. Furlonger, Arumugavadivel Narendran, Haruhiko Suzuki, Pamela S. Ohashi, Christopher J. Paige, Tadatsugu Taniguchi, and Tak W. Mak
	Title	Targeted Disruption of IRF-1 or IRF-2 Results in Abnormal Type I IFN Gene Induction and Aberrant Lymphocyte Development
	Journal	Cell
	Volume	75
	Page	83-97
	Year	1993
	PMID	8402903

Disease , Applicable field information

OMIM

OMIM ID: 147576
Human Gene Symbol: IRF2

OMIM ID: 147574
Human Gene Symbol: IRF9