Center for Animal Resources and Development Database ! Home About CARD  
Strains
Genes
Reference
Disease
Download
Distribution
Home > Strains > Strain detail

Strain Detail


 - Strains   - Genes   - Reference 
 Strain information
  CARD ID
2034 
Type of strain Targeted mutant. 
Strain name C57BL/6-Hbegf tm1 
Internal Code HBhz 
Submitter Unknown Unknown 
Submitter affiliation or code  
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization Osaka University, Research Institute for Microbial Diseases 
Organization code  
Developer Eisuke Mekada 
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
Hbegf 
Gene name heparin-binding EGF-like growth factor 
Allele symbol Hbegftm1 
Allele name heparin-binding EGF-like growth factor, targeted mutation 1 
MGI MGI:96070 
Chromosome 18 (19.46 ) 
Gene classification Targeted or trapped gene(knockout etc.) 
Method  
OMIM
 
 Primer 1
  PCR Primer Intron3 Fw3  CAT GGG GTT GTG ACT CTC CT 
Intron3 Rev3  AGC CTG CAC ACA CAA AAG TG 
 
 Primer 2
  PCR Primer GFP Fwd  CAA GCA GAT CCT GAA GAA CA 
GFP Rev  GAA CAT CTC CTC GAT CAG GT 
 

 Reference information
 reference information 1
  Author
Tomoko Ichise1, Satoshi Adachi1, Minako Ohishi1, Masahito Ikawa2, Masaru Okabe2, Ryo Iwamoto1, and Eisuke Mekada 
Title Humanized gene replacement in mice reveals the contribution of cancer stroma-derived HB-EGF to tumor growth 
Journal  
Volume  
Page  
Year  
PMID