| |
CARD ID
 |
249 |
| Type of strain |
Transgenic. |
| Strain name |
B6;BALB-Tg(0.6hTTRMet30)14Imeg |
| Internal Code |
|
| Submitter |
Ken-ichi YAMAMURA |
| Submitter affiliation or code |
Center for Animal Resources and Development Kumamoto University |
| Stock Type |
|
| Material Transfer Conditions |
It is necessary to consent to the submitter.
|
| Production method |
In-house breading.
|
Origin
(In-house) |
Organization |
Institute for Molecular Embryology and Genetics |
| Organization code |
IMEG |
| Developer |
Ken-ichi Yamamura |
Origin
(From other organizations) |
Organization |
|
| Organization code |
|
| Developer |
|
| Year introduced |
|
Introduced
Generation |
|
| Remarks |
|
| |
Gene symbol
|
Ttr |
| Gene name |
transthyretin Val 30 Met (Human) |
| Allele symbol |
|
| Allele name |
|
| MGI |
MGI:98865 |
| Chromosome |
Unknown |
| Gene classification |
Gene to express(transgenic) |
| Method |
|
| GO |
|
| OMIM |
OMIM ID:
176300
Human Gene Symbol:
TTR
|
| GO |
|
|
| |
PCR Primer |
primerA
|
5'(TCTCACGTGTCTTCTCTACA)3'
|
|
primerB
|
3'(AGCCTCTCTCTACCAAGTGA)5'
|
|
| reference information 1 |
| |
Author
|
Hiromitsu Noguchi, Tadashi Kaname, Tomohisa Sekimoto, Kei Senba, Yasushi Nagata, Masatake Araki, Makoto Abe, Naomi Nakagata, Tomomichi Ono, Ken-ichi Yamamura and Kimi Araki |
| Title |
Naso-maxillary deformity due to frontonasal expression of human transthyretin gene in transgenic mice |
| Journal |
Genes to Cells |
| Volume |
7 |
| Page |
1087-1098 |
| Year |
2002 |
|
PMID
|
12354101
|
|
|
Disease , Applicable field information
|
| |
Disease name,
Applicable field
|
Development
|
| |
OMIM |
OMIM ID:
176300
Human Gene Symbol:
TTR
Allelic Variant Name :
| • |
AMYLOIDOSIS, OCULOLEPTOMENINGEAL |
| • |
TRANSTHYRETIN ACIDIC ASN-90 VARIANT |
| • |
AMYLOID POLYNEUROPATHY, JEWISH TYPE |
| • |
AMYLOIDOSIS, LEPTOMENINGEAL |
| • |
HYPERTHYROXINEMIA, FAMILIAL DYSPREALBUMINEMIC EUTHYROID |
| • |
AMYLOID POLYNEUROPATHY |
| • |
AMYLOIDOSIS, SENILE |
| • |
AMYLOIDOSIS, SYSTEMIC, NEUROPATHIC, AND LEPTOMENINGEAL |
| • |
AMYLOID POLYNEUROPATHY, RUKAVINA OR INDIANA TYPE |
| • |
AMYLOIDOSIS, CARDIAC OR DENMARK TYPE |
| • |
AMYLOID POLYNEUROPATHY, MAHLOUDJI OR MARYLAND TYPE |
| • |
AMYLOID POLYNEUROPATHY, ANDRADE OR PORTUGUESE TYPE |
| • |
AMYLOID POLYNEUROPATHY, APPALACHIAN TYPE |
| • |
TRANSTHYRETIN POLYMORPHISM |
| • |
CARPAL TUNNEL SYNDROME, FAMILIAL |
| • |
AMYLOIDOSIS, FAMILIAL |
| • |
AMYLOID CARDIOMYOPATHY |
| • |
PREALBUMIN CHICAGO |
| • |
AMYLOID POLYNEUROPATHY, GERMAN-AMERICAN TYPE |
| • |
TRANSTHYRETIN SER-6 POLYMORPHISM |
|
|
|
