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Strain Detail

 - Strains   - Genes   - Disease,Applicable field 
 Strain information
  CARD ID
 251 
Type of strain Targeted mutant. 
Strain name 129-Ttrtm1 
Internal Code Mshum1,M 
Submitter Unknown Unknown 
Submitter affiliation or code President, Shuichiro Maeda, National University Corporation University of Yamanashi 
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading, From other organizations.
 
Origin
(In-house)		 Organization The First Department of Biochemistry Yamanashi Medical University 
Organization code  
Developer Shuichiro Maeda
Dr. EJ R 
Origin
(From other organizations)		 Organization Columbia University 
Organization code Y4093898B1 
Developer Shuichiro Maeda
Dr. EJ R 
Year introduced August 1993  
Introduced 
Generation		 N1 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
 Ttr 
Gene name transthyretin 
Allele symbol Ttrtm1 
Allele name Ttr, targeted mutation 1 
MGI MGI:98865 
Chromosome 18 (7.0) 
Gene classification Targeted or trapped gene(knockout etc.) 
Method  
GO
GO ID GO Term GO Evidence Code
GO:0005179 hormone activity IEA
GO:0005576 extracellular region IEA
GO:0006810 transport IEA
OMIM OMIM ID: 176300
Human Gene Symbol: TTR

GO
GO ID GO Term GO Evidence Code
GO:0005179 hormone activity IEA
GO:0005576 extracellular region IEA
GO:0006810 transport IEA
 

 Disease , Applicable field information
  Disease name,
Applicable field
Metabolism, Neurobiology, Immunology, Development 
  OMIM OMIM ID: 176300
Human Gene Symbol: TTR
Allelic Variant Name :
•
AMYLOID POLYNEUROPATHY, MAHLOUDJI OR MARYLAND TYPE
•
TRANSTHYRETIN SER-6 POLYMORPHISM
•
AMYLOIDOSIS, SENILE
•
CARPAL TUNNEL SYNDROME, FAMILIAL
•
AMYLOIDOSIS, CARDIAC OR DENMARK TYPE
•
AMYLOID POLYNEUROPATHY, GERMAN-AMERICAN TYPE
•
AMYLOID POLYNEUROPATHY, JEWISH TYPE
•
AMYLOID POLYNEUROPATHY, RUKAVINA OR INDIANA TYPE
•
TRANSTHYRETIN ACIDIC ASN-90 VARIANT
•
AMYLOID POLYNEUROPATHY, APPALACHIAN TYPE
•
AMYLOID POLYNEUROPATHY, ANDRADE OR PORTUGUESE TYPE
•
AMYLOIDOSIS, OCULOLEPTOMENINGEAL
•
AMYLOID CARDIOMYOPATHY
•
AMYLOIDOSIS, FAMILIAL
•
PREALBUMIN CHICAGO
•
AMYLOID POLYNEUROPATHY
•
TRANSTHYRETIN POLYMORPHISM
•
AMYLOIDOSIS, SYSTEMIC, NEUROPATHIC, AND LEPTOMENINGEAL
•
HYPERTHYROXINEMIA, FAMILIAL DYSPREALBUMINEMIC EUTHYROID
•
AMYLOIDOSIS, LEPTOMENINGEAL

 
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