CARD R-BASE ( Mouse Strain Resource )

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CARD

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Strain Detail

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Strain information

	CARD ID		242
	Type of strain		Targeted mutant.
	Strain name		129-Atp6v0c^tm1
	Internal Code		PL16^+/- (Atp6l^+/-) mouse PL16^+/- mouse (Atp6l^+/- mouse)
	Submitter		Hiroki Inoue
	Submitter affiliation or code
	Stock Type
	Material Transfer Conditions		It is necessary to consent to the submitter.
	Production method		In-house breading.
	Origin (In-house)	Organization	Osaka univ.
		Organization code
		Developer	Hiroki Inoue
	Origin (From other organizations)	Organization
		Organization code
		Developer
		Year introduced
		Introduced Generation
	Remarks

Gene information

Gene information 1

Gene symbol

Atp6v0c

Gene name

ATPase, H+ transporting, V0 subunit C

Allele symbol

Atp6v0c^tm1

Allele name

Atp6v0c, targeted mutation 1

MGI

Chromosome

17

Gene classification

Targeted or trapped gene(knockout etc.)

Method

GO

GO ID	GO Term	GO Evidence Code
GO:0033179	proton-transporting V-type ATPase, V0 domain	IEA
GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)	IEA
GO:0015986	ATP synthesis coupled proton transport	IEA
GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain	IEA
GO:0006810	transport	IEA
GO:0015992	proton transport	IEA
GO:0005773	vacuole	IEA
GO:0006811	ion transport	IEA
GO:0016020	membrane	IEA
GO:0016021	integral to membrane	IEA
more... (Total Hit Count: 16)

OMIM

OMIM ID: 108745
Human Gene Symbol: ATP6V0C

GO

GO ID	GO Term	GO Evidence Code
GO:0033179	proton-transporting V-type ATPase, V0 domain	IEA
GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)	IEA
GO:0015986	ATP synthesis coupled proton transport	IEA
GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain	IEA
GO:0006810	transport	IEA
GO:0015992	proton transport	IEA
GO:0005773	vacuole	IEA
GO:0006811	ion transport	IEA
GO:0016020	membrane	IEA
GO:0016021	integral to membrane	IEA
more... (Total Hit Count: 16)

Primer 1

	PCR Primer	primerA	5'(TTGCCTCCTCGCTCGCTGTCCCGTT)3'
		primerB	3'(CTGACCCGTGTTGTCTGTTAGCCGA)5'

Reference information

reference information 1

	Author	Hiroki Inoue, Takato Noumi, Mitsuo Nagata, Hiroshi Murakami, Hiroshi Kanazawa
	Title	Targeted disruption of the gene encoding the proteolipid subunit of mouse vacuolar H⁺-ATPase leads to early embryonic lethality
	Journal	BIOCHIMICA ET BIOPHYSICA ACTA
	Volume	1413
	Page	130-138
	Year	1999
	PMID	10556625

Disease , Applicable field information

	Disease name, Applicable field	Development
	OMIM	OMIM ID: 108745 Human Gene Symbol: ATP6V0C