| |
CARD ID
 |
635 |
| Type of strain |
Transgenic. |
| Strain name |
B6;C-Tg(CD2-PKCA)1Clhs |
| Internal Code |
PKC α Tg mouse |
| Submitter |
KAWAMOTO Yoshiyuki |
| Submitter affiliation or code |
Chubu University Research Institute of Life and Health Sciences |
| Stock Type |
|
| Material Transfer Conditions |
It is necessary to consent to the submitter.
|
| Production method |
In-house breading.
|
Origin
(In-house) |
Organization |
Nagoya University School of Medicine |
| Organization code |
|
| Developer |
IWAMOTO, Takashi |
Origin
(From other organizations) |
Organization |
|
| Organization code |
|
| Developer |
|
| Year introduced |
|
Introduced
Generation |
|
| Remarks |
|
| |
Gene symbol
|
PKCA |
| Gene name |
Protein Kinase C, alpha |
| Allele symbol |
|
| Allele name |
|
| MGI |
|
| Chromosome |
Unknown |
| Gene classification |
Gene to express(transgenic) |
| Method |
MicroInjection |
| OMIM |
OMIM ID:
176960
Human Gene Symbol:
PRKCA
|
|
| reference information 1 |
| |
Author
|
Kozo Ohkusu, Jun Du, Ken-Ichi Isobe, Hong Yi, Anwarul A. Akhand, Masashi Kato, Haruhiko Suzuki, Hiroyoshi Hidaka, and Izumi Nakashima |
| Title |
Protein Kinase Cα-Mediated Chronic Signal Transduction for Immunosenescence1 |
| Journal |
The Journal of Immunology |
| Volume |
159 |
| Page |
2082-2084 |
| Year |
1997 |
|
PMID
|
|
|
| reference information 2 |
| |
Author
|
Takashi Iwamoto, Masatoshi Hagiwara, Hiroyoshi Hidaka, Takeshi Isomura, Dimitris Kioussis, and Izumi Nakashima |
| Title |
Accelerated Proliferation and Interleukin-2 Production of Thymocytes by Stimulation of Soluble Anti-CD3 Monoclonal Antibody in Transgenic Mice Carrying a Rabbit Protein Kinase Cα |
| Journal |
THE JOURNAL OF BIOLOGICAL CHEMISTRY |
| Volume |
267 |
| Page |
18644-18648 |
| Year |
1992 |
|
PMID
|
|
|
|
Disease , Applicable field information
|
| |
Disease name,
Applicable field
|
cancer, Immunology
|
| |
OMIM |
OMIM ID:
176960
Human Gene Symbol:
PRKCA
Allelic Variant Name :
| • |
PITUITARY TUMOR, INVASIVE, SOMATIC |
|
|
|
