| |
CARD ID
 |
1813 |
| Type of strain |
Targeted mutant. |
| Strain name |
B6;129-Mll1tm1.1Mlc |
| Internal Code |
MlldC |
| Submitter |
Yokoyama Akihiko |
| Submitter affiliation or code |
Kyoto University Graduate School of Medicine Medical Innovation Center Laboratory for Malignancy Control Research DSK project |
| Stock Type |
|
| Material Transfer Conditions |
It is necessary to consent to the submitter.
|
| Production method |
From other organizations.
|
Origin
(In-house) |
Organization |
|
| Organization code |
|
| Developer |
|
Origin
(From other organizations) |
Organization |
Stanford University Medical School |
| Organization code |
Mlc |
| Developer |
Michael L. Cleary |
| Year introduced |
May
2009
|
Introduced
Generation |
|
| Remarks |
|
| |
Gene symbol
|
Mll1 |
| Gene name |
myeloid/lymphoid or mixed-lineage leukemia 1 |
| Allele symbol |
Mll1tm1.1Mlc |
| Allele name |
myeloid/lymphoid or mixed-lineage leukemia 1; targeted mutation 1.1, Michael L Cleary |
| MGI |
MGI:96995 |
| Chromosome |
9 (24.84) |
| Gene classification |
Targeted or trapped gene(knockout etc.) |
| Method |
Electroporation |
| OMIM |
|
|
| |
PCR Primer |
dC&uc.fwd
|
gttctgaagcacacattccacacc
|
|
dC&uc.rev
|
catcaaagcgaagggcaatcagtg
|
|
| reference information 1 |
| |
Author
|
Yokoyama, A., Ficara, F., Murphy, M. J., Meisel, C., Naresh, A., Kitabayashi, I. and Cleary, M. L. |
| Title |
Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways. |
| Journal |
J Cell Sci |
| Volume |
124 |
| Page |
2208-2219 |
| Year |
2011 |
|
PMID
|
|
|
|
Disease , Applicable field information
|
| |
Disease name,
Applicable field
|
Hematology, Endocrine Disorders, cancer, Cell biology, Molecular biology, Aging
|
|
|
