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Strain Detail


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 Strain information
  CARD ID
577 
Type of strain Targeted mutant. 
Strain name B6.129-Jak3tm1CARD 
Internal Code Jak 3 KO
B6.129-Jak3tm1CARD 
Submitter Unknown Unknown 
Submitter affiliation or code  
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method From other organizations.
 
Origin
(In-house)
Organization  
Organization code  
Developer Takashi Saito 
Origin
(From other organizations)
Organization Takashi Saito 
Organization code  
Developer  
Year introduced January 2004  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
Jak3 
Gene name Janus kinase 3,The Institute of Physical and Chemical Research,RIKEN 
Allele symbol Jak3tm1Rik 
Allele name targeted mutation 1 
MGI MGI:99928 
Chromosome 8 (33) 
Gene classification Targeted or trapped gene(knockout etc.) 
Method  
OMIM OMIM ID: 600173
Human Gene Symbol: JAK3

 

 Reference information
 reference information 1
  Author
Seung Yong Park, Kaoru Saijo, Takamune Takahashi, Masatake Osawa, Hisashi Arase, Nakami Hirayama, Keiko Miyake, Hiromitsu Nakauchi, Takuji Shirasawa, and Takashi Saito 
Title Developmental Defects of Lymphoid Cells in Jak3 Kinase-Deficient Mice 
Journal Immunity 
Volume
Page 771-782 
Year 1995 
PMID 8777722  
 
 Disease , Applicable field information
  Disease name,
Applicable field
Immunology, Development 
  OMIM OMIM ID: 600173
Human Gene Symbol: JAK3
Allelic Variant Name :
SEVERE COMBINED IMMUNODEFICIENCY, AUTOSOMAL RECESSIVE, T CELL-NEGATIVE,