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Strain Detail


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 Strain information
  CARD ID
292 
Type of strain Spontaneous/Chemical induced mutant. 
Strain name C3101F1-Pax6Sey-3H 
Internal Code
 
Submitter Nitta Yumiko 
Submitter affiliation or code Ros.Inst. Radiat.Biot.Med., Hiroshima University 
Stock Type  
Material Transfer Conditions No condition. 
 
Production method From other organizations.
 
Origin
(In-house)
Organization  
Organization code  
Developer  
Origin
(From other organizations)
Organization MRC 
Organization code  
Developer B. M. Cattanach 
Year introduced October 2000  
Introduced 
Generation
F2 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
Pax6 
Gene name paired box gene 6 
Allele symbol  
Allele name  
MGI MGI:97490 
Chromosome 2 (58.0cM) 
Gene classification Other gene(mutant etc.) 
Method  
GO
GO ID GO Term GO Evidence Code
GO:0005634 nucleus IDA
GO:0006350 transcription IEA
GO:0005667 transcription factor complex TAS
GO:0003700 transcription factor activity TAS, IDA
GO:0003677 DNA binding IDA
GO:0007275 multicellular organismal development IEA
GO:0030154 cell differentiation IMP
GO:0007411 axon guidance IMP
GO:0030334 regulation of cell migration IMP
GO:0008285 negative regulation of cell proliferation IMP
more... (Total Hit Count: 57)
OMIM OMIM ID: 607108
Human Gene Symbol: PAX6

GO
GO ID GO Term GO Evidence Code
GO:0005634 nucleus IDA
GO:0006350 transcription IEA
GO:0005667 transcription factor complex TAS
GO:0003700 transcription factor activity TAS, IDA
GO:0003677 DNA binding IDA
GO:0007275 multicellular organismal development IEA
GO:0030154 cell differentiation IMP
GO:0007411 axon guidance IMP
GO:0030334 regulation of cell migration IMP
GO:0008285 negative regulation of cell proliferation IMP
more... (Total Hit Count: 57)
 

 Reference information
 reference information 1
  Author
Yumiko Nitta, Kazuko Yoshida, Kimio Tanaka, Jo Peters and Bruce M. Cattanach 
Title The Mouse Small Eye Mutant, Del(2)Sey3H, Which Deletes the Putative Tumor Suppressor Region of the Radiation-induced Acute Myeloid Leukemia is Susceptible to Radiation. 
Journal  
Volume  
Page  
Year  
PMID  
 
 Disease , Applicable field information
  Disease name,
Applicable field
cancer, Development 
  OMIM OMIM ID: 607108
Human Gene Symbol: PAX6
Allelic Variant Name :
FOVEAL HYPOPLASIA WITH ANTERIOR SEGMENT ANOMALIES
FOVEAL HYPOPLASIA AND PRESENILE CATARACT SYNDROME
PETERS ANOMALY
KERATITIS, AUTOSOMAL DOMINANT
ANIRIDIA
ECTOPIA PUPILLAE
OPTIC NERVE HYPOPLASIA, BILATERAL
COLOBOMA OF OPTIC NERVE
OPTIC NERVE APLASIA, BILATERAL
FOVEAL HYPOPLASIA, ISOLATED
ANIRIDIA, CEREBELLAR ATAXIA, AND MENTAL DEFICIENCY
MORNING GLORY DISC ANOMALY
CATARACTS, CONGENITAL, WITH LATE-ONSET CORNEAL DYSTROPHY