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Strain Detail


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 Strain information
  CARD ID
3010 
Type of strain Targeted mutant. 
Strain name BRJ-Ins2em1Kuma 
Internal Code BRJ(BALB/c;Rag2-/-;Jak3-/-); Ins2Kuma 
Submitter Kume Shoen 
Submitter affiliation or code
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
For non-profit, please cite the following publication. Sakano D, Inoue A, Enomoto T, Imasaka M, Okada S, Yokota M, Koike M, Araki K, Kume S. Insulin2 Q104del (Kuma) Mutant Mice Develop Diabetes with Dominant Inheritance, Sci, Reports 2020. 10(1):12187 doi: 10.1038/s41598-020-68987-z. For profit-making organization, MTA is required. 
Production method In-house breading.
 
Origin
(In-house)
Organization Tokyo Institute of Technology 
Organization code  
Developer Shoen Kume 
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
Ins2 
Gene name insulin II 
Allele symbol Ins2em1Kuma 
Allele name insulin II; endonuclease-mediated mutation 1, 
MGI MGI:96573 
Chromosome 7 (88.00) 
Gene classification Targeted or trapped gene(knockout etc.) 
Method  
OMIM
 

 Reference information
 reference information 1
  Author
Airi Inoue, Takayuki Enomoto, Mai Imasaka, Seiji Okada, Mutsumi Yokota, Masato Koike, Kimi Araki, Shoen Kume 
Title Insulin2 Q104del (Kuma) Mutant Mice Develop Diabetes with Dominant Inheritance 
Journal Scientific Reports 
Volume 10(1) 
Page 12187 
Year 2020 
PMID  
 
 Disease , Applicable field information
  Disease name,
Applicable field
Metabolism, Endocrine Disorders