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Strain Detail


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 Strain information
  CARD ID
644 
Type of strain Targeted mutant. 
Strain name B6;CB-A4galttm1/Card 
Internal Code Gb3KO 
Submitter Koichi Furukawa 
Submitter affiliation or code  
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method From other organizations.
 
Origin
(In-house)
Organization  
Organization code  
Developer  
Origin
(From other organizations)
Organization Naoki Takeda 
Organization code Card 
Developer Center for Animal Resources and Development 
Year introduced April 2003  
Introduced 
Generation
F1 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
A4galt 
Gene name alpha 1,4-galactosyltransferase 
Allele symbol  
Allele name  
MGI  
Chromosome 15 (E2 ) 
Gene classification Targeted or trapped gene(knockout etc.) 
Method Electroporation
MicroInjection 
OMIM
 
 Primer 1
  PCR Primer Neo-F1  CGT GAT ATT GCT GAA GAG CTT GGC GGC GAA 
77KO-R1  GAA CTC ATG CTT GCG CTC GAA GGC TAG GAA 
 

 Reference information
 reference information 1
  Author
Tetsuya Okuda, Noriyo Tokuda, Shin-ichiro Numata, Masafumi Ito, Michio Ohta, Kumiko Kawamura, Joelle Wiels, Takeshi Urano, Orie Tajima, Keiko Furukawa, and Koichi Furukawa 
Title Targeted Disruption of Gb3/CD77 Synthase Gene Resulted in the Complete Deletion of Globo-series Glycosphingolipids and Loss of Sensitivity to Verotoxins 
Journal J. Biol. Chem. 
Volume 281 
Page 10230-10235 
Year 2006 
PMID  
 
 Disease , Applicable field information
  Disease name,
Applicable field
Metabolism, cancer, Immunology, Development, Physiology