Center for Animal Resources and Development Database ! Home About CARD  
Strains
Genes
Reference
Disease
Download
Distribution
Home > Strains > Strain detail

Strain Detail


 - Strains   - Genes   - Reference   - Disease,Applicable field 
 Strain information
  CARD ID
359 
Type of strain Targeted mutant. 
Strain name B6;129-Adra1dtm1 
Internal Code
B6 α1D-AR-KO 
Submitter Unknown Unknown 
Submitter affiliation or code  
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization  
Organization code  
Developer Tanoue Akito 
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
Adra1d 
Gene name Adrenergic recetor, alpha 1d 
Allele symbol Adra1dtm1 
Allele name Adra1d, targeted mutation 1 
MGI MGI:106673 
Chromosome 2 (74.9) 
Gene classification Targeted or trapped gene(knockout etc.) 
Method Electroporation 
GO
GO ID GO Term GO Evidence Code
GO:0004930 G-protein coupled receptor activity IEA
GO:0016021 integral to membrane IEA
GO:0016020 membrane IEA
GO:0004872 receptor activity IEA
GO:0004871 signal transducer activity IEA
GO:0005886 plasma membrane IEA
GO:0004935 adrenoceptor activity IEA
GO:0007186 G-protein coupled receptor protein signaling pathway IEA
GO:0007165 signal transduction IEA
GO:0004937 alpha1-adrenergic receptor activity IDA
more... (Total Hit Count: 12)
OMIM OMIM ID: 104219
Human Gene Symbol: ADRA1D

GO
GO ID GO Term GO Evidence Code
GO:0004930 G-protein coupled receptor activity IEA
GO:0016021 integral to membrane IEA
GO:0016020 membrane IEA
GO:0004872 receptor activity IEA
GO:0004871 signal transducer activity IEA
GO:0005886 plasma membrane IEA
GO:0004935 adrenoceptor activity IEA
GO:0007186 G-protein coupled receptor protein signaling pathway IEA
GO:0007165 signal transduction IEA
GO:0004937 alpha1-adrenergic receptor activity IDA
more... (Total Hit Count: 12)
 
 Primer 1
  PCR Primer primerA  5'(ACACA,GTCGC,ACTCA,GTAGC,AGGTC,A)3' 
primerB  5'(CCTAC,ATTTT,GAATG,GAAGG,ATTG)3' 
 

 Reference information
 reference information 1
  Author
Akito Tanoue, Yoshihisa Nasa, Takaaki Koshimizu, Hitomi Shinoura, Sayuri Oshikawa, Takayuki Kawai, Sachie Sunada, Satoshi Takeo, and Gozoh Tsujimoto 
Title The α1D-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction 
Journal The Journal of Clinical Investigation 
Volume 109 
Page 765-775 
Year 2002 
PMID 11901185  
 
 Disease , Applicable field information
  Disease name,
Applicable field
Physiology 
  OMIM OMIM ID: 104219
Human Gene Symbol: ADRA1D