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Strain Detail


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 Strain information
  CARD ID
2288 
Type of strain Targeted mutant. 
Strain name B6;129S-Acat1tm1Ishi 
Internal Code ACAT1KO 
Submitter ISHIBASHI SHUN 
Submitter affiliation or code Jichi Medical University 
Stock Type  
Material Transfer Conditions Other conditions. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization  
Organization code Ishi 
Developer Shun Ishibashi 
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
Acat1 
Gene name acetyl-Coenzyme A acetyltransferase 1 
Allele symbol Acat1tm1Ishi 
Allele name acetyl-Coenzyme A acetyltransferase 1, targeted mutation 1, Shun Ishibashi, Jichi Medical University 
MGI MGI:87870 
Chromosome 9 (29.12) 
Gene classification Targeted or trapped gene(knockout etc.) 
Method  
OMIM
 
 Primer 1
  PCR Primer HY30  5'-TCT TGT AAG CTG CTT GTA AGA GTG CC-3' 
HY31  5'-AGC TAG TAA GAA CAG TTC CCT TTC CC-3' 
SI-75  5'-GAT TGG GAA GAC AAT AGC AGG CAT GC-3' 
 

 Reference information
 reference information 1
  Author
Hiroaki Yagyu 
Title Absence of ACAT-1 Attenuates Atherosclerosis but Causes Dry Eye and Cutaneous Xanthomatosis in Mice with Congenital Hyperlipidemia 
Journal JBC 
Volume 275 (28) 
Page 21324-21330 
Year 2000 
PMID