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Strain Detail


 - Strains   - Genes   - Disease,Applicable field   - EGTC 
 Strain information
  CARD ID
1085 
Type of strain Gene trap. 
Strain name B6;CB-AladGt(pU-21T)323Imeg 
Internal Code Ayu21-T323 
Submitter Ken-ichi YAMAMURA 
Submitter affiliation or code Center for Animal Resources and Development Kumamoto University 
Stock Type  
Material Transfer Conditions It is necessary to consent to the submitter. 
 
Production method In-house breading.
 
Origin
(In-house)
Organization Institute of Molecular Embryology and Genetics Kumamoto University 
Organization code  
Developer Kimi Araki 
Origin
(From other organizations)
Organization  
Organization code  
Developer  
Year introduced  
Introduced 
Generation
 
Remarks  
 
 Gene information
 Gene information 1
  Gene symbol
Alad 
Gene name aminolevulinate, delta-, dehydratase 
Allele symbol  
Allele name  
MGI MGI:96853 
Chromosome 4  
Gene classification Targeted or trapped gene(knockout etc.) 
Method Electroporation 
GO
GO ID GO Term GO Evidence Code
GO:0006783 heme biosynthetic process IDA
GO:0016829 lyase activity IEA
GO:0008270 zinc ion binding IEA
GO:0006779 porphyrin biosynthetic process IEA
GO:0003824 catalytic activity IEA
GO:0004655 porphobilinogen synthase activity IDA
GO:0008152 metabolic process IEA
GO:0046872 metal ion binding IEA
GO:0033014 tetrapyrrole biosynthetic process IEA
GO:0042802 identical protein binding IPI
OMIM OMIM ID: 125270
Human Gene Symbol: ALAD

GO
GO ID GO Term GO Evidence Code
GO:0006783 heme biosynthetic process IDA
GO:0016829 lyase activity IEA
GO:0008270 zinc ion binding IEA
GO:0006779 porphyrin biosynthetic process IEA
GO:0003824 catalytic activity IEA
GO:0004655 porphobilinogen synthase activity IDA
GO:0008152 metabolic process IEA
GO:0046872 metal ion binding IEA
GO:0033014 tetrapyrrole biosynthetic process IEA
GO:0042802 identical protein binding IPI
 
 Primer 1
  PCR Primer Z-1  GCGTTACCCAACTTAATCG 
Z-2  TGTGAGCGAGTAACAACC 
 

 Disease , Applicable field information
  Disease name,
Applicable field
Development 
  OMIM OMIM ID: 125270
Human Gene Symbol: ALAD
Allelic Variant Name :
PORPHYRIA, ACUTE HEPATIC
PORPHYRIA, ACUTE HEPATIC, SEVERE INFANTILE-ONSET FORM
AMINOLEVULINATE DEHYDRATASE, ALAD*1/ALAD*2 POLYMORPHISM

 
 Related imformation
  EGTC
21-T323