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Strain Detail

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Strain information

	CARD ID		90
	Type of strain		Targeted mutant.
	Strain name		C57BL/6-Cd19^tm1(Cre)
	Internal Code
	Submitter		Nobuo SAKAGUCHI
	Submitter affiliation or code		Kumamoto University School of Medicine, Department of Immunoloy
	Stock Type
	Material Transfer Conditions		Other conditions.
	Production method		From other organizations.
	Origin (In-house)	Organization
		Organization code
		Developer
	Origin (From other organizations)	Organization	University of California
		Organization code
		Developer	Robert C.Rickert
		Year introduced
		Introduced Generation
	Remarks

Gene information

Gene information 1

Gene symbol

Cd19

Gene name

CD19 antigen

Allele symbol

Allele name

MGI

Chromosome

Gene classification

Targeted or trapped gene(knockout etc.)

Method

Other

GO

GO ID	GO Term	GO Evidence Code
GO:0016021	integral to membrane	IEA
GO:0016020	membrane	IEA
GO:0050853	B cell receptor signaling pathway	IDA
GO:0009897	external side of plasma membrane	IDA

OMIM

GO

GO ID	GO Term	GO Evidence Code
GO:0016021	integral to membrane	IEA
GO:0016020	membrane	IEA
GO:0050853	B cell receptor signaling pathway	IDA
GO:0009897	external side of plasma membrane	IDA

Gene information 2

Gene symbol

Cre

Gene name

Cre recombinase

Allele symbol

Allele name

MGI

Chromosome

7 (59cM)

Gene classification

Targeted or trapped gene(knockout etc.)

Method

Other

GO

GO ID	GO Term	GO Evidence Code
GO:0016021	integral to membrane	IEA
GO:0016020	membrane	IEA
GO:0050853	B cell receptor signaling pathway	IDA
GO:0009897	external side of plasma membrane	IDA

OMIM

GO

GO ID	GO Term	GO Evidence Code
GO:0016021	integral to membrane	IEA
GO:0016020	membrane	IEA
GO:0050853	B cell receptor signaling pathway	IDA
GO:0009897	external side of plasma membrane	IDA

Reference information

reference information 1

	Author	Robert C. Rickert, Jurgen Roes and Klaus Rajewsky
	Title	B Iymphocyte-specific, Cre-mediated mutagenesis in mice
	Journal	Nucleic Acids Research
	Volume	25
	Page	1317-1318
	Year	1997
	PMID	9092650

reference information 2

	Author	Yousuke Takahama, Kazuhito Ohishi, Yayoi Tokoro, Takehiko Sugawara, Yasuhide Yoshimura, Masaru Okabe, Taroh Kinoshita and Junji Takeda
	Title	Functional competence of T cells in the absence of glycosylphosphatidylinositol-anchored proteins caused by T cell-specific disruption of the Pig-a gene
	Journal	Eur. J. Immunol.
	Volume	28
	Page	2159-2166
	Year	1998
	PMID	9692885

reference information 3

	Author	Araki, K., Araki, M., Miyazaki, J. & Vassalli, P.
	Title	Site-Specific Recombination of a Transgene in Fertilized Eggs by Transient Expression of Cre Recombinase
	Journal	Proc. Natl. Acad. Sci. USA
	Volume	92
	Page	160-164
	Year	1995
	PMID	7816809