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Strain Detail

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Strain information

	CARD ID		780
	Type of strain		Transgenic.
	Strain name		B6;C3H-Tg(K19-Wnt1)#7S
	Internal Code		K19-Wnt1
	Submitter		Masanobu Oshima
	Submitter affiliation or code		Division of Genetics, Cancer Research Institute, Kanazawa University
	Stock Type
	Material Transfer Conditions		It is necessary to consent to the submitter.
	Production method		In-house breading.
	Origin (In-house)	Organization	Cancer Research Institute, Kanazawa Univ.
		Organization code
		Developer	Hiroko Oshima
	Origin (From other organizations)	Organization
		Organization code
		Developer
		Year introduced
		Introduced Generation
	Remarks

Gene information

Gene information 1

Gene symbol

Wnt1

Gene name

wingless-related MMTV integration site 1

Allele symbol

Allele name

MGI

Chromosome

Unknown

Gene classification

Gene to express(transgenic)

Method

MicroInjection

GO

GO ID	GO Term	GO Evidence Code
GO:0005576	extracellular region	IEA
GO:0007275	multicellular organismal development	IEA
GO:0005578	proteinaceous extracellular matrix	IEA
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	IEA
GO:0004871	signal transducer activity	IEA
GO:0022004	midbrain-hindbrain boundary maturation during brain development	IMP
GO:0021536	diencephalon development	IGI
GO:0021797	forebrain anterior/posterior pattern formation	IGI
GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter	IDA
GO:0060070	Wnt receptor signaling pathway through beta-catenin	IDA
more... (Total Hit Count: 19)

OMIM

OMIM ID: 164820
Human Gene Symbol: WNT1

GO

GO ID	GO Term	GO Evidence Code
GO:0005576	extracellular region	IEA
GO:0007275	multicellular organismal development	IEA
GO:0005578	proteinaceous extracellular matrix	IEA
GO:0007223	Wnt receptor signaling pathway, calcium modulating pathway	IEA
GO:0004871	signal transducer activity	IEA
GO:0022004	midbrain-hindbrain boundary maturation during brain development	IMP
GO:0021536	diencephalon development	IGI
GO:0021797	forebrain anterior/posterior pattern formation	IGI
GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter	IDA
GO:0060070	Wnt receptor signaling pathway through beta-catenin	IDA
more... (Total Hit Count: 19)

Primer 1

	PCR Primer	Wnt1F	CGACCGTGTTCTCTGAGATG
		HA-R	CATCATATGGGTAGGCCATGG

Reference information

reference information 1

	Author	Oshima H, Matsunaga A, Fujimura T, Tsukamoto T, Taketo MM, Oshima M.
	Title	Carcinogenesis in mouse stomach by simultaneous activation of the wnt signaling and prostaglandin e(2) pathway.
	Journal	Gastroenterology
	Volume	131
	Page	1086-1095
	Year	2006
	PMID

Disease , Applicable field information

	Disease name, Applicable field	cancer
	OMIM	OMIM ID: 164820 Human Gene Symbol: WNT1