| |
CARD ID
 |
1896 |
| Type of strain |
Transgenic. |
| Strain name |
B6;BALB-Tg(Krt19-Wnt1/K19-Ptgs2/K19-Ptges) |
| Internal Code |
B6;BALB-Tg(Krt19-Wnt1/K19-Ptgs2/K19-Ptges), K19-Wnt1/C2mE(B6;BALB) |
| Submitter |
Masanobu Oshima |
| Submitter affiliation or code |
Division of Genetics, Cancer Research Institute, Kanazawa University |
| Stock Type |
|
| Material Transfer Conditions |
Other conditions.
|
| Production method |
In-house breading.
|
Origin
(In-house) |
Organization |
Cancer Research Institute, Kanazawa Univ. |
| Organization code |
|
| Developer |
Masanobu Oshima |
Origin
(From other organizations) |
Organization |
|
| Organization code |
|
| Developer |
|
| Year introduced |
|
Introduced
Generation |
|
| Remarks |
|
| |
Gene symbol
|
Wnt1, Ptgs2, Ptges |
| Gene name |
wingless-type MMTV integration site family, member 1; prostaglandin-endoperoxide synthase 2; prostaglandin E synthase |
| Allele symbol |
|
| Allele name |
|
| MGI |
MGI:98953 |
| Chromosome |
Unknown |
| Gene classification |
Gene to express(transgenic) |
| Method |
MicroInjection |
| OMIM |
OMIM ID:
164820
Human Gene Symbol:
WNT1
OMIM ID:
600262
Human Gene Symbol:
PTGS2
OMIM ID:
605172
Human Gene Symbol:
PTGES
|
|
| |
PCR Primer |
Wnt1F,COX-2-F3
|
CGACCGTGTTCTCTGAGATG,CAAACTCAAGTTTGACCCAG
|
|
HA-R,COX-2-R1
|
CATCATATGGGTAGGCCATGG,CTTTTACAGCTCAGTTGAACG
|
|
| reference information 1 |
| |
Author
|
Oshima H, Matsunaga A, Fujimura T, Tsukamoto T, Taketo MM, Oshima M. |
| Title |
Carcinogenesis in mouse stomach by simultaneous activation of the wnt signaling and prostaglandin e(2) pathway. |
| Journal |
Gastroenterology |
| Volume |
131 |
| Page |
1086-1095 |
| Year |
2006 |
|
PMID
|
|
|
| reference information 2 |
| |
Author
|
Oshima H, Oguma K, Du YC and Oshima M |
| Title |
Prostaglandin E2, Wnt, and BMP in gastric tumor mouse models. |
| Journal |
Cancer Science |
| Volume |
100 (10) |
| Page |
1779-1785 |
| Year |
2009 |
|
PMID
|
|
|
| reference information 3 |
| |
Author
|
Oshima H and Oshima M |
| Title |
Mouse models of gastric tumors: Wnt activation and PGE2 induction. |
| Journal |
Pathology International |
| Volume |
60 (9) |
| Page |
599-607 |
| Year |
2010 |
|
PMID
|
|
|
|
Disease , Applicable field information
|
| |
Disease name,
Applicable field
|
cancer
|
| |
OMIM |
OMIM ID:
164820
Human Gene Symbol:
WNT1
OMIM ID:
600262
Human Gene Symbol:
PTGS2
OMIM ID:
605172
Human Gene Symbol:
PTGES
|
|
|
