Regulation of vasculogenesis and angiogenesis by EphB/ephrin-B2 signaling between endothelial cells and surrounding mesenchymal cells
Cutting Edge: Absence of Expression of RAG1 in Peritoneal B-1 Cells Detected by Knocking into RAG1 Locus with Green Fluorescent Protein Gene
Genetic control of blood pressure and the angiotensinogen locus
The role of Bcl6 in mature cardiac myocytes
The α1D-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction
Cloning of a housekeeping-type gene (MER5) preferentially expressed in murine erythroleukemia cells.
Lymphoproliferative Disorders with Early Lethality in Mice Deficient in Ctla-4
90. A Transgenic Mouse Model of Familial Amyloidotic Polyneuropathy
Targeted disruption of the gene encoding the proteolipid subunit of mouse vacuolar H+-ATPase leads to early embryonic lethality
Expression of Tom34 splicing isoforms in mouse testis and knockout of Tom34 in mice.
Protein Kinase Cα-Mediated Chronic Signal Transduction for Immunosenescence1
Direct Isolation of Committed Neuronal Progenitor Cells From Transgenic Mice Coexpressing Spectrally Distinct Fluorescent Proteins Regulated by Stage-Specific Neural Promoters
Site-Specific Recombination of a Transgene in Fertilized Eggs by Transient Expression of Cre Recombinase
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
Z/EG, a Double Reporter Mouse Line That Expresses Enhanced Green Fluorescent Protein Upon Cre-Mediated Excision
Genetic resistance to urethan-induced pulmonary adenomas in SMXA RI strains mice.
Germ Line Transmission and Expression of a Corrected HPRT Gene Produced by Gene Targeting in Embryonic Stem Cells
Characterization of the murine cytomegalovirus early transcription unit e1 that is induced by immediate-early proteins.
Neuron-Specific Activation of Murine Cytomegalovirus Early Gene e1 Promoter in Transgenic Mice
Pancreatic beta Cell–specific Expression of  Thioredoxin, an Antioxidative and Antiapoptotic Protein, Prevents Autoimmune and Streptozotocin-induced Diabetes
Therapeutic effect of {beta}-adrenoceptor blockers using a mouse model of dilated cardiomyopathy with a troponin mutation.
Elimination of Epiplakin by Gene Targeting Results in Acceleration of Keratinocyte Migration in Mice
Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders (myocardial development/hematopoiesis)
Impaired growth pancreatic exocrine cells in transgenic mice expressing human activin BE subunit
Role of a BCL9-Related Beta-Catenin-Binding Protein, B9L, in Tumorigenesis Induced by Aberrant Activation of Wnt Signaling
Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells.
Nat Immunol
Roles of the Foxj1 and Inv genes in the left-right determination of internal organs in mice.
Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor.
Prostasin attenuates inducible nitric oxide synthase expression in lipopolysaccharide-induced urinary bladder inflammation
Expression of human factors CD81, claudin-1, scavenger receptor, and occluding in mouse hepatocytes does not confer susceptibility to HCV entry.
Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male fertility [corrected].
Lentiviral Vector-Mediated Complementation Restored Fetal Viability but Not Placental Hyperplasia in Plac1-Deficient Mice.
Pyramidal neurons of upper cortical layers generated by NEX-positive progenitor cells in the subventricular zone.
Neonatal bleeding in transgenic mice expressing urokinase-type plasminogen activtor.
Generalized lacZ expression with the ROSA26 Cre reporter strain
Hyperhomocysteinemia abrogates fasting-induced cardioprotection against ischemia/reperfusion by limiting bioavailability of hydrogen sulfide anions.
Death-effector domain-containing protein DEDD is an inhibitor of mitotic Cdk1/cyclin B1.
The death effector domain-containing DEDD forms a complex with Akt and Hsp90, and supports their stability.
Homeobox gene hex is essential for onset of mouse embryonic liver development and differentiation of the monocyte lineage
Premature Aging in Mice Deficient in DNA Repair and Transcription.
Identification of distinct telencephalic progenitor pools for neuronal diversity in the amygdala.
Ablation of Neutral Cholesterol Ester Hydrolase 1 Accelerates Atherosclerosis
Transgenic Expression of a Single Transcription Factor Pdx1 Induces Transdifferentiation of Pancreatic Acinar Cells to Endocrine Cells in Adult Mice.
Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury.
Hemizygosity of transsulfuration genes confers increased vulnerability against acetaminophen-induced hepatotoxicity in mice.
Co-expression of sperm membrane proteins CMTM2A and CMTM2B is essential for ADAM3 localization and male fertility in mice.
Seminal vesicle secretory protein 7, PATE4, is not required for sperm function but for copulatory plug formation to ensure fecundity.
Study of normal and pathological blood vessel morphogenesis in Flt1-tdsRed BAC Tg mice.
Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids.
Testis-enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa
The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs
CRISPR/Cas9-mediated genome-edited mice reveal 10 testis-enriched genes are dispensable for male fecundity
Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm-oocyte fusion in mice.
A Novel Transgenic Technique That Allows Specific Marking of the Neural Crest Cell Lineage in Mice
Differential requirement of the cytoplasmic subregions of γc chain in T cell Development and function
Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia
Mapping Quantitative Trait Loci for Circadian Behavioral Rhythms in SMXA Recombinant Inbred Strains
Targeted Disruption of the Pemphigus Vulgaris Antigen (Desmoglein 3) Gene in Mice Causes Loss of Keratinocyte Cell Adhesion with a Phenotype Similar to Pemphigus Vulgaris
Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel
Bcl-xL Displays Restricted Distribution during T Cell Developement and Inhibits Multiple Forms of Apoptosis but Not Clonal Deletion in Transgenic Mice
Radixin deficiency causes conjugated hyperbilirubinemiawith loss of Mrp2 from bile canalicular membranes.
Heparin-binding EGF-like growth factor and ErbB signaling is essential for heart function
Syndecan-4 Deficiency Impairs Focal Adhesion Formation Only under Restricted Conditions
Characterization of T-cell tolerance to hepatitis B virus in transgenic mice
Distribution of body weight, blood insulin and lipid levels in the SMXA recombinant inbred strains and the QTL analysis.
Transgenic Expression of the Endothelin-B Receptor Prevents Congenital Intestinal Aganglionosis in a Rat Model of Hirschsprung Disease
Islet cell hyperplasia in transgenic mice overexpressing EAT/mcl-1, a bcl-2 related gene
Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis
Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model.
Z/AP, a double reporter for cre-mediated recombination.
Overexpression of Plasma Membrane-associated Sialidase Attenuates Insulin Signaling in Transgenic Mice
Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells.
Marked Perinatal Lethality and Cellular Signaling Deficits in Mice Null for the Two Sphingosine 1-Phosphate (S1P) Receptors, S1P2/LPB2/EDG-5 and S1P3/LPB3/EDG-3
Cardiomyopathy-causing deletion K210 in cardiac troponin T alters phosphorylation propensity of sarcomeric proteins.
Maternal-effect gene Ces5/Ooep/Moep19/Floped is essential for oocyte cytoplasmic lattice formation and embryonic development at the maternal-zygotic stage transition
Age-related pulmonary emphysema in mice lacking a/b hydrolase domain containing 2 gene
Notch2 activation in the embryonic kidney depletes nephron progenitors
Targeted disruption of the cardiac troponin T gene causes sarcomere disassembly and defects in heartbeat within the early mouse embryo.
Embryonic lethality in mismatch-specific thymine DNA glycosylase deficient mice is partially prevented by DOPS, a precursor of noradrenaline
Targeted mutation of the murine goosecoid gene results in craniofacial defects and neonatal death
Smooth muscle-specific dystrophin expression improves aberrant vasoregulation in mdx mice
Six1 controls patterning of the mouse otic vesicle.
Six1 and Six4 promote survival of sensory neurons during early trigeminal gangliogenesis
Human Parvovirus B19 Transgenic Mice Become Susceptible to Polyarthritis
Hyperproduction of hyaluronan in neu-induced mammary tumor accelerates angiogenesis through stromal cell recruitment: possible involvement of versican /PG-M.
Motor Neuron-specific Disruption of Proteasomes, but not Autophagy, Replicates Amyotrophic Lateral Sclerosis.
Spatiotemporal gene control by the Cre-ERT2 system in melanocytes.
Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes
Altered pain perception and inflammatory response in mice lacking prostacyclin receptor
Establishment of Nude mice with complete loss of lymphocytes and NK cells and Application for in vivo bio-imaging.
The Rab8 GTPase regulates apical protein localization in intestinal cells.
Calsperin is a testis-specific chaperone required for sperm fertility
Prostaglandin E2, Wnt, and BMP in gastric tumor mouse models.
Calreticulin is required for development of the cumulus oocyte complex and female fertility.
Neurons limit angiogenesis by titrating VEGF in retina
Phenotypic abnormalities in a chorea-acanthocytosis mouse model are modulated by strain background.
A gene-targeted mouse model for chorea-acanthocytosis.
Sperm postacrosomal WW domain-binding protein is not required for mouse egg activation
C/EBP homologous protein deficiency attenuates myocardial reperfusion injury by inhibiting myocardial apoptosis and inflammation.
Human Globozoospermia-Related Gene Spata16 Is Required for Sperm Formation Revealed by CRISPR/Cas9-Mediated Mouse Models.
Seminal vesicle protein SVS2 is required for sperm survival in the uterus
Liver-Specific Deletion of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Causes Hepatic Steatosis and Death
Death effector domain-containing protein (DEDD) is required for uterine decidualization during early pregnancy in mice.
Function of the acrosomal matrix: zona pellucida 3 receptor (ZP3R/sp56) is not essential for mouse fertilization.
Scavenger Receptor Expressed by Endothelial Cells I (SREC-I) Mediates the Uptake of Acetylated Low Density Lipoproteins by Macrophages Stimulated with Lipopolysaccharide
Neutral aminoaciduria in cystathionine beta-synthase-deficient mice, an animal model of homocystinuria.
An azoospermic factor gene, Ddx3y and its paralog, Ddx3x are dispensable in germ cells for male fertility.
Nexin-Dynein regulatory complex component DRC7 but not FBXL13 is required for sperm flagellum formation and male fertility in mice.
Flk1-GFP BAC Tg mice: an animal model for the study of blood vessel development.
MEIOSIN directs the switch from mitosis to meiosis in mammalian germ cells.
CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in mice
Knockout of serine-rich single-pass membrane protein 1 (Ssmem1) causes globozoospermia and sterility in male mice
Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice
CRISPR/Cas9-Mediated Genome Editing Reveals Oosp Family Genes are Dispensable for Female Fertility in Mice.
Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis
c-fos Expression Interferes with Thymus Development in Transgenic Mice
Reduced hippocampal LTP in mice lacking a presynaptic protein: complexin II
Molecular Cloning and Expression of Mouse Mg2+-Dependent Protein Phosphatase β-4 (Type 2Cβ-4)1
Bone and haematopoietic defects in mice lacking c-fos
E-Selectin Binding Promotes Neutrophil Activation in Vivo in E-Selectin Transgenic Mice
Mammalian antioxidant protein complements alkylhydroperoxide reductase (ahpC) mutation in Escherichia coli.
Site-directed integration of the cre gene mediated by Cre recombinase using a combination of mutant lox sites
A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on receptor biochemistry that results in impaired lactation
Combinations of nondiabetic parental genomes elicit impaired glucose tolerance in mouse SMXA recombinant inbred strains.
HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells
A 6-kb Upstream Region of the Human Transthyretin Gene Can Direct Developmental, Tissue-Specific, and Quantitatively Normal Expression in Transgenic Mouse
A transgenic mouse model for the detailed morphological study of astrocytes
Expression of the receptor for pituitary adenylate cyclase-activating polypeptide (PAC1-R) in reactive astrocytes
Myopathy phenotype in transgenic mice expressing mutated PABPN1 as a model of oculopharyngeal muscular dystrophy
A Transgenic Mouse Line That Retains Cre Recombinase Activity in Mature Oocytes Irrespective of the cre Transgene Transmission
Transgenic Expression of Antioxidant Protein Thioredoxin in Pancreatic beta Cells Prevents Progression of Type 2 Diabetes Mellitus
Carcinogenesis in mouse stomach by simultaneous activation of the wnt signaling and prostaglandin e(2) pathway.
A mouse line expressing Sall1-driven inducible Cre recombinase in the kidney mesenchyme.
The anaphase-promoting complex/cyclosome activator Cdh1 modulates RhoGTPase by targeting p190 RhoGAP for degradation.
Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.
Identification of SCAN Domain Zinc-Finger Gene ZNF449 as a Novel Factor of Chondrogenesis.
GPI-anchored protein complex, LY6K/TEX101, is required for sperm migration into the oviduct and male fertility in mice.
Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoa
Gene expression pattern of Cue110: A member of the uncharacterized UPF0224 gene family preferentially expressed in germ cells
"Color Timer" mice: visualization of neuronal differentiation with fluorescent proteins
A targeted disruption of the CHOP gene protects mice against ER stress-induced diabetes.
CRISPR/Cas9 mediated genome editing in ES cells and its application for chimeric analysis in mice.
The Mg2+ transporter CNNM4 regulates sperm Ca2+ homeostasis and is essential for reproduction.
Sperm-borne phospholipase C zeta-1 ensures monospermic fertilization in mice
Transgenic Mouse Sperm that Have Green Acrosome and Red Mitochondria Allow Visualization of Sperm and Their Acrosome Reaction in Vivo
Parvalbumin neurons in the forebrain as revealed by parvalbumin-Cre transgenic mice.
Frequent spontaneous seizures followed by spatial working memory/anxiety deficits in mice lacking sphingosine 1-phosphate receptor 2.
Methionine excess in diet induces acute lethal hepatitis in mice lacking cystathionine gamma-lyase, an animal model of cystathioninuria.
Cystathionine gamma-lyase-produced hydrogen sulfide controls endothelial NO bioavailability and blood pressure.
Interaction of CD99 with its paralog CD99L2 positively regulates CD99L2 trafficking to cell surfaces.
Six1 is required for signaling center formation and labial-lingual asymmetry in developing lower incisors.
Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm-oocyte fusion in mice
PITHD1 is a proteasome-interacting protein essential for male fertilization.
Prss55 but Not Prss51 Is Required for Male Fertility in Mice
Inflammatory disease and cancer with a decrease in Kupffer cell numbers in Nucling-knockout mice.
Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm−oocyte fusion in mice
Spermatozoa lacking Fertilization Influencing Membrane Protein (FIMP) fail to fuse with oocytes in mice
Molecular and embryological characterization of a new transgene-induced null allele of mouse Brachyury locus.
The Upstream Regulatory Region of the Carbamoyl-phosphate Synthetase I Gene Controls Its Tissue-specific, Developmental, and Hormonal Regulation in Vivo
Immunocytochemical Analyses and Targeted Gene Disruption of GTPBP1
Critical role of the membrane-proximal, proline-rich motif of the interleukin-2 receptor γc chain in the Jak3-independent signal transduction
Targeted Insertion of a Variable Region Gene into the Immunoglobulin Heavy Chain Locus
Essential and non-redundant roles of p48 (ISGF3γ)and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies
'Green mice' as a source of ubiquitous green cells
Chromosomal mapping of the host resistance locus to rodent malaria (Plasmodium yoelii) infection in mice
Human CLC-KB Gene Promoter Drives the EGFP Expression in the Specific Distal Nephron Segments and Inner Ear.
Disruption of the midkine gene (Mdk) resulted in altered expression of a calcium binding protein in the hippocampus of infant mice and their abnormal behaviour
A Transgenic Mouse Line That Retains Cre Recombinase Activity in Mature Oocytes lrrespective of the cre Transgene Transmission
Efficiency of Recombination by Cre Transient Expression in Embryonic Stem Cells: Comparison of Various Promoters
Genetic profile of the SMXA recombinant inbred mouse strain revealed with restriction landmark genomic scanning.
H-2Haplotypes of Strains DBR7, B10.NZW, NFS, BQ2, STU, TO1, and TO2
Fine chromosomal localization of the mouse Par2 gene that confers resistance against urethane-induction of pulmonary adenomas
Expression and replication of hepatitis B virus genome in transgenic mice
Expression of p300 protects cardiac myocytes from apoptosis in vivo
Functional Role of Type I and Type II Interferons in Antiviral Defense
Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes
Ectopic expression of the bHLH gene Math1 disturbs neural development.
Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells
VWRPY motif-dependent and -independent roles of AML1/Runx1 transcription factor in murine hematopoietic development
A study of functional role of perilipin in lipid metabolism
Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype
High-level expression of viral interleukin-10 in cardiac allografts fails to prolong graft survival
The Basic Helix-Loop-Helix Factor Olig2 Is Essential for the Development of Motoneuron and Oligodendrocyte Lineages
Cystathionine gamma-Lyase-deficient Mice Require Dietary Cysteine to Protect against Acute Lethal Myopathy and Oxidative Injury
Knock-in mouse model of dilated cardiomyopathy caused by troponin mutation.
Galectin-8 modulates neutrophil function via interaction with integrin alphaM.
Mice Lacking M2 and M3 Muscarinic Acetylcholine Receptors Are Devoid of Cholinergic Smooth Muscle Contractions But Still Viable
The vasopressin V1b receptor critically regulates hypothalamic-pituitary-adrenal axis activity under both stress and resting conditions
Six4 a putative myogenin gene regulator, is not essential for mouse embryonal development.
Dullard/Ctdnep1 modulates WNT signaling activity for the formation of primordial germ cells in the mouse embryo.
Prostaglandin D2 as a mediator of allergic asthma.
A Runx1 intronic enhancer marks hemogenic endothelial cells and hematopoietic stem cells.
Wild-type measles virus infection in human CD46/CD150-transgenic mice: CD11c-positive dendritic cells establish systemic viral infection.
Fatal propionic acidemia in mice lacking propionyl-CoA carboxylase and its rescue by postnatal, liver-specific supplementation via a transgene.
Long-term Oral Administration of Hop Flower Extracts Mitigates Alzheimer Phenotypes in Mice
Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice
CRISPR/Cas9-mediated mutation revealed cytoplasmic tail is dispensable for IZUMO1 function and male fertility
Ectopic Expression of GIP in Pancreatic beta-Cells Maintains Enhanced Insulin Secretion in Mice With Complete Absence of Proglucagon-Derived Peptides.
Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway.
Cappuccino Mutation in an Autoimmune-Prone Strain of Mice
MTSS1 Regulation of Actin-Nucleating Formin DAAM1 in Dendritic Filopodia Determines Final Dendritic Configuration of Purkinje Cells.
LPA5 signaling is involved in multiple sclerosis-mediated neuropathic pain in the cuprizone mouse model.
Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice
Abcb10 role in heme biosynthesis in vivo: Abcb10 knockout in mice causes anemia with protoporphyrin IX and iron accumulation
Aromatase-null mice expressing enhanced green fluorescent protein in germ cells provide a model system to assess estrogen-dependent ovulatory responses
Cerebellar Granule Cell-Specific and Inducible Expression of Cre Recombinase in the Mouse
PHF7 Modulates BRDT Stability and Histone-to-Protamine Exchange during Spermiogenesis
CRISPR/CAS9-mediated amino acid substitution reveals phosphorylation residues of RSPH6A are not essential for male fertility in mice
Tesmin, Metallothionein-Like 5, is Required for Spermatogenesis in Mice
Dissection of the effects of tumor necrosis factor-α and class II gene polymorphisms within the MHC on murine systemic lupus erythematosus (SLE)
RAG-2-Deficient Mice Lack Mature Lymphocytes Owing to Inability to Initiate V(D)J Rearrangement
Expression of Nonspecific Esterase (NSE) by Thyroid Follicular Epithelium as a Marker for the Target Organ Susceptibility to Immune System Attack
Genetic remodeling of gangliosides resulted in the enhanced reactions to the foreign substances in skin
A Transgenic Mouse Expressing Human CYP4B1 in the Liver
Genetic basis and molecular mechanism for idiopathic ventricular fibrillation
Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin-2 Receptor β
Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer
Suppression of Concanavalin A induced hepatitis in IFN- Symbol g Times -/-, but not in TNF- Symbol a Times -/-, mice: role for IFN- Symbol g Times in activating apoptosis of hepatocytes J. Immunol.
Antisense RNA of the latent period gene (MER5) inhibits the differentiation of murine erythroleukemia cells.
Midkine Is Involved in Neutrophil Infiltration into the Tubulointerstitium in Ischemic Renal Injury
Pre-TCR signaling components trigger transcriptional activation of a rearranged TCRα gene locus and silencing of the pre-TCRα locus: implications for intrathymic differentiation
LFA-1-deficient Mice Show Normal CTL Responses to Virus but Fail to Reject Immunogenic Tumor
Targeted and Natural (Piebald-Lethal) Mutations of Endothelin-B Receptor Gene Produce Megacolon Associated with Spotted Coat Color in Mice
Truncated CBP protein leads to classical Rubinstein-Taybi syndrome phenotypes in mice: implications for a dominant-negative mechanism
Tissue-Specific and Developmental Expression of Human Transthyretin Gene in Transgenic Mice
T Cell Receptor Antagonist Peptides Induce Positive Selection
Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development
Cardiac p300 Is Involved in Myocyte Growth with Decompensated Heart Failure
Accelerated Proliferation and Interleukin-2 Production of Thymocytes by Stimulation of Soluble Anti-CD3 Monoclonal Antibody in Transgenic Mice Carrying a Rabbit Protein Kinase Cα
The testicular fatty acid binding protein PERF15 regulates the fate of germ cells in PERF15 transgenic mice
Autophagic cell death of pancreatic acinar cells in serine protease inhibitor kazal type 3-deficient mice.
Loss of anti-cataleptic effect of scopolamine in mice lacking muscarinic acetylcholine receptor subtype 4
CLC-3 deficiency leads to phenotypes similar to human neuronal ceroid lipofuscinosis
Application of the RLGS image analysis tool (RAT) to the construction of a genetic linkage map of recombinant inbred strain SMXA.
Mouse models for Hirschsprung's disease and Malignant melanoma
Zinc Finger Protein Sall2 Is Not Essential for Embryonic and Kidney Development
Genetic tracing of the gustatory and trigeminal neural pathways originating from T1R3-expressing taste receptor cells and solitary chemoreceptor cells
Involvement of the Olig2 transcription factor in cholinergic neuron development of the basal forebrain
Correlation of tissue-specific methylation with gene inactivity in hepatitis B virus transgenic mice.
Postsynaptic M1 and M3 receptors are responsible for the muscarinic enhancement of retrograde endocannabinoid signalling in the hippocampus
Hyperplastic gastric tumors induced by activated macrophages in COX-2/mPGES-1 transgenic mice
Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways.
Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice.
Targeted Deletion of the Calcineurin Inhibitor DSCR1 Suppresses Tumor Growth
Sall4 is essential for stabilization, but not pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression.
Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor.
Impaired maturation of myeloid progenitors in mice lacking novel Polycomb group protein MBT-1.
A novel reporter mouse strain that expresses enhanced green fluorescent protein upon Cre-mediated recombination.
Subtypes of GABAergic neurons project axons in the neocortex.
Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization
Gtsf1/Cue110, a gene encoding a protein with two copies of a CHHC Zn-finger motif, is involved in spermatogenesis and retrotransposon suppression in murine testes
A Mouse Model for the basal Transcription/DNA Repair Syndrome Trichothiodystrophy
A Signal Adaptor SLAM-Associated Protein Regulates
A Cre Knock-In Mouse Line on the Sickle Tail Locus Induces Recombination in the Notochord and Intervertebral Disks.
Regulated expression of pdx-1 promotes in vitro differentiation of insulin-producing cells from embryonic stem cells.
S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species.
RSPH6A is required for sperm flagellum formation and male fertility in mice.
CD99-Dependent Expansion of Myeloid-Derived Suppressor Cells and Attenuation of Graft-Versus-Host Disease.
MEIOSIN directs the switch from mitosis to meiosis in mammalian germ cells
CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice.
A CK19CreERT knockin mouse line allows for conditional DNA recombination in epithelial cells in multiple endodermal organs.
Two transgenic approaches to define the cell lineages in endocrine pancreas development.
A meiosis-specific factor C19orf57/4930432K21Rik/BRME1 modulates localization of RAD51 and DMC1 recombinases to DSBs in mouse meiotic recombination.
Calaxin is required for cilia-driven determination of vertebrate laterality
Visualization of PAX7 protein dynamics in muscle satellite cells in a YFP knock-in-mouse line
ARMC12 regulates spatiotemporal mitochondrial dynamics during spermiogenesis and is required for male fertility
Requirement of H-2 heterozygosity for autoimmunity in (NZB x NZW)F1 hybrid mice
FISH Analysis of 142 EGFP Transgene Integration Sites into the Mouse Genome
The SMXA : a new set of recombinant inbred strain of mice consisting of 26 substrains and their genetic profile.
Feasibility of gene therapy using human OSF1 against osteoporosis
Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons
Neointima formation in a restenosis model is suppressed in midkine-deficient mice
Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5
Genetic analysis of mortality in murine Angiostrongyliasis costaricensis using SMXA recombinant inbred mouse strains.
Genetic analysis of resistance to radiation lymphomagenesis with recombinant inbred strains of mice
Improved strain distribution patterns of SMXA recombinant inbred strains by microsatellite markers.
Resistance of STS/A mice to lymphoma induction by X-irradiation.
Chronic active hepatitis in transgenic mice expressing interferon-γ in the liver
Liver-Specific and High-Level Expression of Human Serum Amyloid P Component Gene in Transgenic Mice
Bone Mass Loss Due to Estrogen Deficiency Is Compensated in Transgenic Mice Overexpressing Human Osteoblast Stimulating Factor-11
A Novel Pathogenesis of Megacolon in Ncx/Hox11L.1 Deficient Mice
Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements
Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-/ Gene Induction
Targeted Disruption of Gb3/CD77 Synthase Gene Resulted in the Complete Deletion of Globo-series Glycosphingolipids and Loss of Sensitivity to Verotoxins
Redirection of Tumor Metastasis by Expression of E-Selectin In Vivo
Apical localization of renal K channel was not altered in mutant WNK4 transgenic mice
Induction and Down-regulation of Sox17 and Its Possible Roles During the Course of Gastrointestinal Tumorigenesis
Olig2-positive progenitors in the embryonic spinal cord give rise not only to motoneurons and oligodendrocytes, but also to a subset of astrocytes and ependymal cells
Murine Cytomegalovirus Immediate-Early Promoter Directs Astrocyte-Specific Expression in Transgenic Mice
Increase of smooth muscle cell migration and of intimal hyperplasia in mice lacking the a/b hydrolase domain containing 2 gene
Development of highly stable galectins: truncation of the linker peptide confers protease-resistance on tandem-repeat type galectins.
Targeted disruption of the Tab1 gene causes embryonic lethality and defects in cardiovascular and lung morphogenesis
Sperm postacrosomal WW domain-binding protein is not required for mouse egg activation.
The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specitic gene expression during inflammation in mice
The Calcineurin-NFAT-Angiopoietin-2 Signaling Axis in Lung Endothelium ls Critical for the Establishment of Lung Metastases
Ets Motifs Are Necessary for Endothelial Cell-Specific Expression of a 723-bp Tie-2 Promoter/Enhancer in Hprt Targeted Transgenic Mice
Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice.
Sall4 is essential for stabilization, but not pluripotency, of embryonic stem cells by repressing aberrant trophectoderm gene expression.
Humanized gene replacement in mice reveals the contribution of cancer stroma-derived HB-EGF to tumor growth
A novel therapeutic molecule against HTLV-1 infection targeting provirus.
The zinc finger gene Fezf2 is required for the development of excitatory neurons in the basolateral complex of the amygdala.
The error-prone DNA polymerase i provides quantitative resistance to lung tumorigenesis and mutagenesis in mice
Genetic tracing of the gustatory neural pathway originating from Pkd1l3-expressing type III taste cells in circumvallate and foliate papillae
The Endoplasmic Reticulum Stress-CHOP Pathway-mediated Apoptosis in Macrophages Contributes to the Instability of Atherosclerotic Plaques.
Activation of the receptor tyrosine kinase Kit is required for the proliferation of melanoblasts in the mouse embryo.
miR-200b and miR-429 function in mouse ovulation and are essential for female fertility.
Plasma cholesterol-lowering and transient liver dysfunction in mice lacking squalene synthase in the liver.
Genetic background conversion ameliorates semi-lethality and permits behavioral analyses in cystathionine beta-synthase-deficient mice, an animal model for hyperhomocysteinemia.
The death effector domain-containing DEDD supports S6K1 activity via preventing Cdk1-dependent inhibitory phosphorylation.
Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA.
Targeted Deletion of Both Thymidine Phosphorylase and Uridine Phosphorylase and Consequent Disorders in Mice
A novel murine gene, Sickle tail, linked to the Danforth's short tail locus, is required for normal development of the intervertebral disc.
Absence of ACAT-1 Attenuates Atherosclerosis but Causes Dry Eye and Cutaneous Xanthomatosis in Mice with Congenital Hyperlipidemia
Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates high-fat diet-induced adipocyte hypertrophy and systemic glucose intolerance in mice.
Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates streptozotocin-induced apoptosis of pancreatic beta-cells.
Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis.
The testis-specific serine proteases Prss44, Prss46, and Prss54 are dispensable for mouse fertility.
MiR-142 is required for Staphylococcus aureus clearance at skin wound sites via small GTPase-mediated regulation of the neutrophil actin cytoskeleton.
Increased Urinary 3-Mercaptolactate Excretion and Enhanced Passive Systemic Anaphylaxis in Mice Lacking Mercaptopyruvate Sulfurtransferase, a Model of Mercaptolactate-Cysteine Disulfiduria.
CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
Meiotic cohesins mediate initial loading of HORMAD1 to the chromosomes and coordinate SC formation during meiotic prophase.
CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction
NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility
Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice.
CIB4 is essential for the haploid phase of spermatogenesis in mice
SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice
Functional Analysis of Novel Candidate Regulators of Insulin Secretion in the MIN6 Mouse Pancreatic beta Cell Line
An Autosomal Dominant Mutation of Facial Development in a Transgenic Mouse
Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells.
Cardiac Na+ Channel Dysfunction in Brugada Syndrome Is Aggravated by β1-Subunit
Cross Talk Between Interferon-γ and -α/β Signaling Components in Caveolar Membrane Domains
Requirement of CD9 on the Egg Plasma Membrane for Fertilization
Loss of connexin45 causes a cushion defect in early cardiogenesis
Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development
A NewTransgenic Mouse Mutagenesis Test System Using Spi- and 6-Thioguanine Selections
Decreased blood pressure response in mice deficient of the α1b-adrenergic receptor
mTOR Is Essential for Growth and Proliferation in Early Mouse Embryos and Embryonic Stem Cells
Complete antithrombin deficiency in mice results in embryonic lethality
Identification and minisatellite linkage analysis os SMXA recombinant inbred strains of mice by DNA fingerprinting.
Sequence and structural organization of murine cytomegalovirus immediate-early gene 1.
Fgf16 is required for cardiomyocyte proliferation in the mouse embryonic heart.
Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1
Targeted disruption of the mouse ELYS gene results in embryonic death at peri-implantation development
Destruction of Pancreatic β-Cells by Transgenic Induction of Prostaglandin E2 in the Islets
Pathogenesis and treatment of autosomal-dominant nephrogenic diabetes insipidus caused by an aquaporin 2 mutation
Tangential migration and proliferation of intermediate progenitors of GABAergic neurons in the mouse telencephalon
Spatial genetic patterning of the neuroepithelium generates GABAergic interneuron diversity in the adult cortex
Ectopic expression of Ptf1a induces spinal defects, urogenital defects, and anorectal malformations in Danforth's short tail mice.
Rab8a and Rab8b are essential for multiple apical transport pathways but insufficient for ciliogenesis
Slc25a13-knockout mice harbor
Molecular Identification of tw5: Vps52 Promotes Pluripotential Cell Differentiation through Cell–Cell Interactions
Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions.
CABYR is essential for fibrous sheath integrity and progressive motility in mouse spermatozoa
DiGeorge syndrome phenotype in mice mutant for the T-box gene, Tbx1
Angiopoietins contribute to lung development by regulating pulmonary vascular network formation
Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice
Targeted disruption of hormon-sensitive lipaseresults in male sterility and adipocyte hypertrophy, but not in obesity
Embryonic Lethality and Defective Neural Tube Closure in Mice Lacking Squalene Synthase
Acinar-to-ductal metaplasia induced by adenovirus-mediated pancreatic expression of Isl1.
Deletion of GIRK2 subunit containing GIRK channels of neurons expressing dopamine transporter decrease immobility time on forced swimming in mice
WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome.
Endothelial CD99 supports arrest of mouse neutrophils in venules and binds to neutrophil PILRs.
Testis-enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa.
Meikin is a conserved regulator of meiosis-I-specific kinetochore function
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors.
Insulin2 Q104del (Kuma) Mutant Mice Develop Diabetes with Dominant Inheritance
Tmprss12 is required for sperm motility and uterotubal junction migration in mice
Mice Homozygous for a Truncated Form of CREB-Binding Protein Exhibit Defects in Hematopoiesis and Vasculo-angiogenesis
Porcine MCP Gene Promoter Directs High Level Expression of Human DAF (CD55) in Transgenic Mice
Disturbed CD4+ T Cell Homeostasis and In Vitro HIV-1 Susceptibility in Transgenic Mice Expressing T Cell Line-tropic HIV-1 Receptors
The Mouse Small Eye Mutant, Del(2)Sey3H, Which Deletes the Putative Tumor Suppressor Region of the Radiation-induced Acute Myeloid Leukemia is Susceptible to Radiation.
c-Jun is essential for normal mouse development and hepatogenesis
Functional analysis of the chondroitin 6-sulfotransferase gene in relation to lymphocyte subpopulations, brain development, and oversulfated chondroitin sulfates.
Naso-maxillary deformity due to frontonasal expression of human transthyretin gene in transgenic mice
Reversible Defects in Natural Killer and Memory CD8 T Cell Lineages in Interleukin 15-deficient Mice
Differential T Cell Costimulatory Requirements in CD28-Deficient Mice
Mutant Mice Lacking Crk-II Caused by the Gene Trap Insertional Mutagenesis: Crk-II Is Not Essential for Embryonic Development
Nestin-EGFP Transgenic Mice: Visualization of the Self-Renewal and Multipotency of CNS Stem Cells
Mice Lacking p27Kip1 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors
Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands
Targeted Disruption of IRF-1 or IRF-2 Results in Abnormal Type I IFN Gene Induction and Aberrant Lymphocyte Development
Parp-1 deficiency causes an increase of deletion mutations and insertions/ rearrangements in vivo after treatment with an alkylating agent
Protein phosphatase subunit G5PR is needed for inhibition of B cell receptor-induced apoptosis
BCR signal through α4 is involved in S6 kinase activation and required for B cell maturation including isotype switching and V region somatic hypermutation
Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice
B Iymphocyte-specific, Cre-mediated mutagenesis in mice
Functional competence of T cells in the absence of glycosylphosphatidylinositol-anchored proteins caused by T cell-specific disruption of the Pig-a gene
Developmental Defects of Lymphoid Cells in Jak3 Kinase-Deficient Mice
HLA-B51 transgenic mice as recipients for production of polymorphic HLA-A, B-specific antibodies
Aberrant melanogenesis and melanocytic tumour development in transgenic mice that carry a metallothionein/ret fusion gene
Strain difference of the adrenal cortex between A/J and SM/J mice,progenitors of SMXA recombinant inbred group.
S-SCAMα is a Scaffold to Mediate NMDA Receptor-denpendent RhoA Activation in Dendries.
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice.
Selective Loss of Sphingosine 1-Phosphate Signaling with No Obvious Phenotypic Abnormality in Mice Lacking Its G Protein-coupled Receptor,LPB3/EDG-3
Up-regulation of type 2 iodothyronine deiodinase in dilated cardiomyopathy.
Alkalinization of Acrosome Measured by GFP as a pH Indicator and Its Relation to Sperm Capacitation
Expression pattern of serine protease inhibitor kazal type 3 (Spink3) during mouse embryonic development.
M3 muscarinic acetylcholine receptor plays a critical role in parasympathetic control of salivation in mice
Identification of a link between Wnt/beta-catenin signaling and the cell fusion pathway
Significance of tumor-associated stroma in promotion of intratumoral lymphangiogenesis : pivotal role of a hyaluronan-rich tumor
Failure of parturition in mice lacking the prostaglandin F receptor.
Mouse models of gastric tumors: Wnt activation and PGE2 induction.
Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive.
GANP suppresses DNA recombination measured by direct-repeat beta-galactosidase gene-construct but not the immunoglobulin-gene-type recombination in mammalian cells.
The Role of PKD in Cell Polarity, Biosynthetic Pathways, and Organelle/F-actin Distribution.
CRISPR/Cas9-Mediated Rapid Generation of Multiple Mouse Lines Identified Ccdc63 as Essential for Spermiogenesis.
TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa
The regulation of membrane cofactor protein (CD46) expression by the 3' untranslated region in transgenic mice.
Quanatitative analysis of membrane cofactor protein (MCP) of complement: High expression of MCP on human leukemia cell lines, which is down-regulated during cell-differentiation.
Functional redundancy of protein kinase D1 and protein kinase D2 in neuronal polarity.
The floor plate is sufficient for development of the sclerotome and spine without the notochord.
The Skt gene, required for anorectal development, is a candidate for a molecular marker of the cloacal plate.
Development of a single-cassette system for spatiotemporal gene regulation in mice.
Lvrn expression is not critical for mouse placentation.
Genetic mutation of Frem3 does not cause Fraser syndrome in mice.
Determining c-Myb Protein Levels Can Isolate Functional Hematopoietic Stem Cell Subtypes
Nine genes abundantly expressed in the epididymis are not essential for male fecundity in mice.
Arrest of spermatogenesis in mice expressing an active heat shock transcription factor 1
Bi-allelic DNAH8 Variants Lead to Multiple Morphological Abnormalities of the Sperm Flagella and Primary Male Infertility
Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis
CRISPR/Cas9-mediated genome editing reveals 12 testis-enriched genes dispensable for male fertility in mice